Intranasal gene therapy to prevent infection by SARS-CoV-2 variants

SARS-CoV-2 variants have emerged with enhanced pathogenicity and transmissibility, and escape from pre-existing immunity, suggesting first-generation vaccines and monoclonal antibodies may now be less effective. Here we present an approach for preventing clinical sequelae and the spread of SARS-CoV-...

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Detalles Bibliográficos
Autores principales: Sims, Joshua J., Greig, Jenny A., Michalson, Kristofer T., Lian, Sharon, Martino, R. Alexander, Meggersee, Rosemary, Turner, Kevin B., Nambiar, Kalyani, Dyer, Cecilia, Hinderer, Christian, Horiuchi, Makoto, Yan, Hanying, Huang, Xin, Chen, Shu-Jen, Wilson, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282039/
https://www.ncbi.nlm.nih.gov/pubmed/34265018
http://dx.doi.org/10.1371/journal.ppat.1009544

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