Cargando…
Increased mitochondrial protein import and cardiolipin remodelling upon early mtUPR
Mitochondrial defects can cause a variety of human diseases and protective mechanisms exist to maintain mitochondrial functionality. Imbalances in mitochondrial proteostasis trigger a transcriptional program, termed mitochondrial unfolded protein response (mtUPR). However, the temporal sequence of e...
Autores principales: | Poveda-Huertes, Daniel, Taskin, Asli Aras, Dhaouadi, Ines, Myketin, Lisa, Marada, Adinarayana, Habernig, Lukas, Büttner, Sabrina, Vögtle, F.-Nora |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282050/ https://www.ncbi.nlm.nih.gov/pubmed/34214073 http://dx.doi.org/10.1371/journal.pgen.1009664 |
Ejemplares similares
-
An Early mtUPR: Redistribution of the Nuclear Transcription Factor Rox1 to Mitochondria Protects against Intramitochondrial Proteotoxic Aggregates
por: Poveda-Huertes, Daniel, et al.
Publicado: (2020) -
mtUPR Modulation as a Therapeutic Target for Primary and Secondary Mitochondrial Diseases
por: Cilleros-Holgado, Paula, et al.
Publicado: (2023) -
Author's View: a nuclear transcription factor relocalizing to mitochondria rescues cells from proteotoxic aggregates
por: Taskin, Asli Aras, et al.
Publicado: (2019) -
Discovery of Genes Activated by the Mitochondrial Unfolded Protein Response (mtUPR) and Cognate Promoter Elements
por: Aldridge, Jonathan E., et al.
Publicado: (2007) -
Auraptene Enhances Junction Assembly in Cerebrovascular Endothelial Cells by Promoting Resilience to Mitochondrial Stress through Activation of Antioxidant Enzymes and mtUPR
por: Lee, Min Joung, et al.
Publicado: (2021)