Advanced maternal age causes premature placental senescence and malformation via dysregulated α‐Klotho expression in trophoblasts

Advanced maternal age (AMA) pregnancy is associated with higher risks of adverse perinatal outcomes, which may result from premature senescence of the placenta. α‐Klotho is a well‐known antiaging protein; however, its expression and effect on the placenta in AMA pregnancies have not yet been fully e...

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Detalles Bibliográficos
Autores principales: Chen, Zhi, Xiong, Liling, Jin, Huili, Yu, Jiaxiao, Li, Xin, Fu, Huijia, Wen, Li, Qi, Hongbo, Tong, Chao, Saffery, Richard, Kilby, Mark D., Baker, Philip N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282245/
https://www.ncbi.nlm.nih.gov/pubmed/34105233
http://dx.doi.org/10.1111/acel.13417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282245/
https://www.ncbi.nlm.nih.gov/pubmed/34105233
http://dx.doi.org/10.1111/acel.13417

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