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Advanced maternal age causes premature placental senescence and malformation via dysregulated α‐Klotho expression in trophoblasts
Advanced maternal age (AMA) pregnancy is associated with higher risks of adverse perinatal outcomes, which may result from premature senescence of the placenta. α‐Klotho is a well‐known antiaging protein; however, its expression and effect on the placenta in AMA pregnancies have not yet been fully e...
Autores principales: | Chen, Zhi, Xiong, Liling, Jin, Huili, Yu, Jiaxiao, Li, Xin, Fu, Huijia, Wen, Li, Qi, Hongbo, Tong, Chao, Saffery, Richard, Kilby, Mark D., Baker, Philip N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282245/ https://www.ncbi.nlm.nih.gov/pubmed/34105233 http://dx.doi.org/10.1111/acel.13417 |
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