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Novel mouse model expands potential human α-cell research
A glucagon knock-out mouse with preserved GLP-1 and GLP-2 secretion allows for the improved study of transplanted human islets and glucagon responses— providing an unprecedented resource in human α-cell and diabetes research
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282280/ https://www.ncbi.nlm.nih.gov/pubmed/33853502 http://dx.doi.org/10.1080/19382014.2021.1914507 |
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author | dos Santos, Theodore MacDonald, Patrick E. |
author_facet | dos Santos, Theodore MacDonald, Patrick E. |
author_sort | dos Santos, Theodore |
collection | PubMed |
description | A glucagon knock-out mouse with preserved GLP-1 and GLP-2 secretion allows for the improved study of transplanted human islets and glucagon responses— providing an unprecedented resource in human α-cell and diabetes research |
format | Online Article Text |
id | pubmed-8282280 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-82822802021-08-02 Novel mouse model expands potential human α-cell research dos Santos, Theodore MacDonald, Patrick E. Islets Commentary A glucagon knock-out mouse with preserved GLP-1 and GLP-2 secretion allows for the improved study of transplanted human islets and glucagon responses— providing an unprecedented resource in human α-cell and diabetes research Taylor & Francis 2021-04-14 /pmc/articles/PMC8282280/ /pubmed/33853502 http://dx.doi.org/10.1080/19382014.2021.1914507 Text en © 2021 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. |
spellingShingle | Commentary dos Santos, Theodore MacDonald, Patrick E. Novel mouse model expands potential human α-cell research |
title | Novel mouse model expands potential human α-cell research |
title_full | Novel mouse model expands potential human α-cell research |
title_fullStr | Novel mouse model expands potential human α-cell research |
title_full_unstemmed | Novel mouse model expands potential human α-cell research |
title_short | Novel mouse model expands potential human α-cell research |
title_sort | novel mouse model expands potential human α-cell research |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282280/ https://www.ncbi.nlm.nih.gov/pubmed/33853502 http://dx.doi.org/10.1080/19382014.2021.1914507 |
work_keys_str_mv | AT dossantostheodore novelmousemodelexpandspotentialhumanacellresearch AT macdonaldpatricke novelmousemodelexpandspotentialhumanacellresearch |