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Novel mouse model expands potential human α-cell research

A glucagon knock-out mouse with preserved GLP-1 and GLP-2 secretion allows for the improved study of transplanted human islets and glucagon responses— providing an unprecedented resource in human α-cell and diabetes research

Detalles Bibliográficos
Autores principales: dos Santos, Theodore, MacDonald, Patrick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282280/
https://www.ncbi.nlm.nih.gov/pubmed/33853502
http://dx.doi.org/10.1080/19382014.2021.1914507
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author dos Santos, Theodore
MacDonald, Patrick E.
author_facet dos Santos, Theodore
MacDonald, Patrick E.
author_sort dos Santos, Theodore
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description A glucagon knock-out mouse with preserved GLP-1 and GLP-2 secretion allows for the improved study of transplanted human islets and glucagon responses— providing an unprecedented resource in human α-cell and diabetes research
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spelling pubmed-82822802021-08-02 Novel mouse model expands potential human α-cell research dos Santos, Theodore MacDonald, Patrick E. Islets Commentary A glucagon knock-out mouse with preserved GLP-1 and GLP-2 secretion allows for the improved study of transplanted human islets and glucagon responses— providing an unprecedented resource in human α-cell and diabetes research Taylor & Francis 2021-04-14 /pmc/articles/PMC8282280/ /pubmed/33853502 http://dx.doi.org/10.1080/19382014.2021.1914507 Text en © 2021 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Commentary
dos Santos, Theodore
MacDonald, Patrick E.
Novel mouse model expands potential human α-cell research
title Novel mouse model expands potential human α-cell research
title_full Novel mouse model expands potential human α-cell research
title_fullStr Novel mouse model expands potential human α-cell research
title_full_unstemmed Novel mouse model expands potential human α-cell research
title_short Novel mouse model expands potential human α-cell research
title_sort novel mouse model expands potential human α-cell research
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282280/
https://www.ncbi.nlm.nih.gov/pubmed/33853502
http://dx.doi.org/10.1080/19382014.2021.1914507
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