Acid-base transporters and pH dynamics in human breast carcinomas predict proliferative activity, metastasis, and survival

Breast cancer heterogeneity in histology and molecular subtype influences metabolic and proliferative activity and hence the acid load on cancer cells. We hypothesized that acid-base transporters and intracellular pH (pH(i)) dynamics contribute inter-individual variability in breast cancer aggressiv...

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Detalles Bibliográficos
Autores principales: Toft, Nicolai J, Axelsen, Trine V, Pedersen, Helene L, Mele, Marco, Burton, Mark, Balling, Eva, Johansen, Tonje, Thomassen, Mads, Christiansen, Peer M, Boedtkjer, Ebbe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282339/
https://www.ncbi.nlm.nih.gov/pubmed/34219652
http://dx.doi.org/10.7554/eLife.68447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282339/
https://www.ncbi.nlm.nih.gov/pubmed/34219652
http://dx.doi.org/10.7554/eLife.68447

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