Engineering skeletal muscle tissues with advanced maturity improves synapse formation with human induced pluripotent stem cell-derived motor neurons

To develop effective cures for neuromuscular diseases, human-relevant in vitro models of neuromuscular tissues are critically needed to probe disease mechanisms on a cellular and molecular level. However, previous attempts to co-culture motor neurons and skeletal muscle have resulted in relatively i...

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Detalles Bibliográficos
Autores principales: Santoso, Jeffrey W., Li, Xiling, Gupta, Divya, Suh, Gio C., Hendricks, Eric, Lin, Shaoyu, Perry, Sarah, Ichida, Justin K., Dickman, Dion, McCain, Megan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282350/
https://www.ncbi.nlm.nih.gov/pubmed/34286174
http://dx.doi.org/10.1063/5.0054984

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