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LRRK2 Kinase Inhibitor Rejuvenates Oxidative Stress-Induced Cellular Senescence in Neuronal Cells

BACKGROUND: Leucine-rich repeat kinase 2 (LRRK2) plays a critical role in the pathogenesis of Parkinson's disease (PD). Aging is the most critical risk factor for the progression of PD. The correlation between aging and cellular senescence has been established. Cellular senescence is correlated...

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Detalles Bibliográficos
Autores principales:	Ho, Dong Hwan, Nam, Daleum, Seo, Mi Kyoung, Park, Sung Woo, Seol, Wongi, Son, Ilhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282384/ https://www.ncbi.nlm.nih.gov/pubmed/34306319 http://dx.doi.org/10.1155/2021/9969842

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