Ethics and regulatory considerations for the clinical translation of somatic cell human epigenetic editing

Altering the human epigenome with gene-editing technology in attempt to treat a variety of diseases and conditions seems scientifically feasible. We explore some of the ethical and regulatory issues related to the clinical translation of human epigenetic editing arguing that such approaches should b...

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Detalles Bibliográficos
Autores principales: Zeps, Nikolajs, Lysaght, Tamra, Chadwick, Ruth, Erler, Alexandre, Foo, Roger, Giordano, Simona, San Lai, Poh, Schaefer, G. Owen, Xafis, Vicki, Chew, Wei Leong, Sugarman, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Forum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282462/
https://www.ncbi.nlm.nih.gov/pubmed/34214486
http://dx.doi.org/10.1016/j.stemcr.2021.06.004
Descripción
Sumario:Altering the human epigenome with gene-editing technology in attempt to treat a variety of diseases and conditions seems scientifically feasible. We explore some of the ethical and regulatory issues related to the clinical translation of human epigenetic editing arguing that such approaches should be considered akin to somatic therapies.

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