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Ethics and regulatory considerations for the clinical translation of somatic cell human epigenetic editing
Altering the human epigenome with gene-editing technology in attempt to treat a variety of diseases and conditions seems scientifically feasible. We explore some of the ethical and regulatory issues related to the clinical translation of human epigenetic editing arguing that such approaches should b...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282462/ https://www.ncbi.nlm.nih.gov/pubmed/34214486 http://dx.doi.org/10.1016/j.stemcr.2021.06.004 |
| _version_ | 1783723019202461696 |
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| author | Zeps, Nikolajs Lysaght, Tamra Chadwick, Ruth Erler, Alexandre Foo, Roger Giordano, Simona San Lai, Poh Schaefer, G. Owen Xafis, Vicki Chew, Wei Leong Sugarman, Jeremy |
| author_facet | Zeps, Nikolajs Lysaght, Tamra Chadwick, Ruth Erler, Alexandre Foo, Roger Giordano, Simona San Lai, Poh Schaefer, G. Owen Xafis, Vicki Chew, Wei Leong Sugarman, Jeremy |
| author_sort | Zeps, Nikolajs |
| collection | PubMed |
| description | Altering the human epigenome with gene-editing technology in attempt to treat a variety of diseases and conditions seems scientifically feasible. We explore some of the ethical and regulatory issues related to the clinical translation of human epigenetic editing arguing that such approaches should be considered akin to somatic therapies. |
| format | Online Article Text |
| id | pubmed-8282462 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-82824622021-07-21 Ethics and regulatory considerations for the clinical translation of somatic cell human epigenetic editing Zeps, Nikolajs Lysaght, Tamra Chadwick, Ruth Erler, Alexandre Foo, Roger Giordano, Simona San Lai, Poh Schaefer, G. Owen Xafis, Vicki Chew, Wei Leong Sugarman, Jeremy Stem Cell Reports Forum Altering the human epigenome with gene-editing technology in attempt to treat a variety of diseases and conditions seems scientifically feasible. We explore some of the ethical and regulatory issues related to the clinical translation of human epigenetic editing arguing that such approaches should be considered akin to somatic therapies. Elsevier 2021-07-01 /pmc/articles/PMC8282462/ /pubmed/34214486 http://dx.doi.org/10.1016/j.stemcr.2021.06.004 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Forum Zeps, Nikolajs Lysaght, Tamra Chadwick, Ruth Erler, Alexandre Foo, Roger Giordano, Simona San Lai, Poh Schaefer, G. Owen Xafis, Vicki Chew, Wei Leong Sugarman, Jeremy Ethics and regulatory considerations for the clinical translation of somatic cell human epigenetic editing |
| title | Ethics and regulatory considerations for the clinical translation of somatic cell human epigenetic editing |
| title_full | Ethics and regulatory considerations for the clinical translation of somatic cell human epigenetic editing |
| title_fullStr | Ethics and regulatory considerations for the clinical translation of somatic cell human epigenetic editing |
| title_full_unstemmed | Ethics and regulatory considerations for the clinical translation of somatic cell human epigenetic editing |
| title_short | Ethics and regulatory considerations for the clinical translation of somatic cell human epigenetic editing |
| title_sort | ethics and regulatory considerations for the clinical translation of somatic cell human epigenetic editing |
| topic | Forum |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282462/ https://www.ncbi.nlm.nih.gov/pubmed/34214486 http://dx.doi.org/10.1016/j.stemcr.2021.06.004 |
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