Uncoupling key determinants of hematopoietic stem cell engraftment through cell-specific and temporally controlled recipient conditioning

Hematopoietic stem cells (HSCs) are typically characterized by transplantation into irradiated hosts in a highly perturbed microenvironment. Here, we show that selective and temporally controlled depletion of resident HSCs through genetic deletion of Gata2 constitutes efficient recipient conditionin...

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Detalles Bibliográficos
Autores principales: Miharada, Natsumi, Rydström, Anna, Rak, Justyna, Larsson, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282468/
https://www.ncbi.nlm.nih.gov/pubmed/34171287
http://dx.doi.org/10.1016/j.stemcr.2021.05.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282468/
https://www.ncbi.nlm.nih.gov/pubmed/34171287
http://dx.doi.org/10.1016/j.stemcr.2021.05.019

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