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Probiotic supplementation reduces inflammatory profiles but does not prevent oral immune perturbations during SIV infection
HIV/SIV infections lead to massive loss of mucosal CD4 + T cells and breakdown of the epithelial mucosa resulting in severe microbial dysbiosis and chronic immune activation that ultimately drive disease progression. Moreover, disruption of one of the most understudied mucosal environments, the oral...
Autores principales: | Jones, Rhianna, Kroll, Kyle, Broedlow, Courtney, Schifanella, Luca, Smith, Scott, Hueber, Brady, Shah, Spandan V., Ram, Daniel R., Manickam, Cordelia, Varner, Valerie, Klatt, Nichole R., Reeves, R. Keith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282626/ https://www.ncbi.nlm.nih.gov/pubmed/34267278 http://dx.doi.org/10.1038/s41598-021-93918-x |
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