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Copper catalyzed late-stage C(sp(3))-H functionalization of nitrogen heterocycles
Nitrogen heterocycle represents a ubiquitous skeleton in natural products and drugs. Late-stage C(sp(3))-H bond functionalization of N-heterocycles with broad substrate scope remains a challenge and of particular significance to modern chemical synthesis and pharmaceutical chemistry. Here, we demons...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282657/ https://www.ncbi.nlm.nih.gov/pubmed/34267229 http://dx.doi.org/10.1038/s41467-021-24671-y |