Effect of the mitochondrial unfolded protein response on hypoxic death and mitochondrial protein aggregation

Mitochondria are the main oxygen consumers in cells and as such are the primary organelle affected by hypoxia. All hypoxia pathology presumably derives from the initial mitochondrial dysfunction. An early event in hypoxic pathology in C. elegans is disruption of mitochondrial proteostasis with induc...

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Detalles Bibliográficos
Autores principales: Yan, Junyi, Sun, Chun-Ling, Shin, Seokyung, Van Gilst, Marc, Crowder, C. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282665/
https://www.ncbi.nlm.nih.gov/pubmed/34267182
http://dx.doi.org/10.1038/s41419-021-03979-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282665/
https://www.ncbi.nlm.nih.gov/pubmed/34267182
http://dx.doi.org/10.1038/s41419-021-03979-z

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