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Effect of the mitochondrial unfolded protein response on hypoxic death and mitochondrial protein aggregation
Mitochondria are the main oxygen consumers in cells and as such are the primary organelle affected by hypoxia. All hypoxia pathology presumably derives from the initial mitochondrial dysfunction. An early event in hypoxic pathology in C. elegans is disruption of mitochondrial proteostasis with induc...
Autores principales: | Yan, Junyi, Sun, Chun-Ling, Shin, Seokyung, Van Gilst, Marc, Crowder, C. Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282665/ https://www.ncbi.nlm.nih.gov/pubmed/34267182 http://dx.doi.org/10.1038/s41419-021-03979-z |
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