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Folic acid fortification of double fortified salt

The addition of folic acid to Double Fortified Salt (with iron and iodine) aims to simultaneously ameliorate three major micronutrient deficiencies in vulnerable populations. To make Triple Fortified Salt, we added folic acid to the iodine solution (first method) and the iron premix (second method)...

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Autores principales: Modupe, Oluwasegun, Siddiqui, Juveria, Jonnalagadda, Akhila, Diosady, Levente L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282793/
https://www.ncbi.nlm.nih.gov/pubmed/34267239
http://dx.doi.org/10.1038/s41598-021-93194-9
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author Modupe, Oluwasegun
Siddiqui, Juveria
Jonnalagadda, Akhila
Diosady, Levente L.
author_facet Modupe, Oluwasegun
Siddiqui, Juveria
Jonnalagadda, Akhila
Diosady, Levente L.
author_sort Modupe, Oluwasegun
collection PubMed
description The addition of folic acid to Double Fortified Salt (with iron and iodine) aims to simultaneously ameliorate three major micronutrient deficiencies in vulnerable populations. To make Triple Fortified Salt, we added folic acid to the iodine solution (first method) and the iron premix (second method) that are used to fortify salt with iron and iodine. When added through the solution, sodium carbonate was needed to dissolve folic acid and to adjust pH. Alternately, folic acid was added either to the iron core or sandwiched between the core and TiO(2) layer of the iron premix. Folic acid and iodine were stable in all cases, retaining more than 70% of the added micronutrients after six months at 45 °C/60–70% relative hu. Adding folic acid to the premix's iron core is preferred as folic acid retention was slightly higher, and the added folic acid did not impact the salt's colour. The additional cost for adding the micronutrients to salt is about 27¢/person per year. Folic acid in the fortified salt made with the preferred method was stable in cooking and did not affect selected cooked foods' sensory properties. The technology is a cost-effective approach for simultaneously combating iron, iodine, and folic acid deficiencies.
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spelling pubmed-82827932021-07-19 Folic acid fortification of double fortified salt Modupe, Oluwasegun Siddiqui, Juveria Jonnalagadda, Akhila Diosady, Levente L. Sci Rep Article The addition of folic acid to Double Fortified Salt (with iron and iodine) aims to simultaneously ameliorate three major micronutrient deficiencies in vulnerable populations. To make Triple Fortified Salt, we added folic acid to the iodine solution (first method) and the iron premix (second method) that are used to fortify salt with iron and iodine. When added through the solution, sodium carbonate was needed to dissolve folic acid and to adjust pH. Alternately, folic acid was added either to the iron core or sandwiched between the core and TiO(2) layer of the iron premix. Folic acid and iodine were stable in all cases, retaining more than 70% of the added micronutrients after six months at 45 °C/60–70% relative hu. Adding folic acid to the premix's iron core is preferred as folic acid retention was slightly higher, and the added folic acid did not impact the salt's colour. The additional cost for adding the micronutrients to salt is about 27¢/person per year. Folic acid in the fortified salt made with the preferred method was stable in cooking and did not affect selected cooked foods' sensory properties. The technology is a cost-effective approach for simultaneously combating iron, iodine, and folic acid deficiencies. Nature Publishing Group UK 2021-07-15 /pmc/articles/PMC8282793/ /pubmed/34267239 http://dx.doi.org/10.1038/s41598-021-93194-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Modupe, Oluwasegun
Siddiqui, Juveria
Jonnalagadda, Akhila
Diosady, Levente L.
Folic acid fortification of double fortified salt
title Folic acid fortification of double fortified salt
title_full Folic acid fortification of double fortified salt
title_fullStr Folic acid fortification of double fortified salt
title_full_unstemmed Folic acid fortification of double fortified salt
title_short Folic acid fortification of double fortified salt
title_sort folic acid fortification of double fortified salt
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282793/
https://www.ncbi.nlm.nih.gov/pubmed/34267239
http://dx.doi.org/10.1038/s41598-021-93194-9
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