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Three-dimensional CRISPR screening reveals epigenetic interaction with anti-angiogenic therapy

Angiogenesis underlies development, physiology and pathogenesis of cancer, eye and cardiovascular diseases. Inhibiting aberrant angiogenesis using anti-angiogenic therapy (AAT) has been successful in the clinical treatment of cancer and eye diseases. However, resistance to AAT inevitably occurs and...

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Detalles Bibliográficos
Autores principales: He, Michael Y., Halford, Michael M., Liu, Ruofei, Roy, James P., Grant, Zoe L., Coultas, Leigh, Thio, Niko, Gilan, Omer, Chan, Yih-Chih, Dawson, Mark A., Achen, Marc G., Stacker, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282794/
https://www.ncbi.nlm.nih.gov/pubmed/34267311
http://dx.doi.org/10.1038/s42003-021-02397-3