Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber

We presented a development of a custom lead shield and mouse strainer for targeted irradiation from the gamma-cell chamber. This study was divided into two parts i.e., to (i) fabricate the shield and strainer from a lead (Pb) and (ii) optimize the irradiation to the mice-bearing tumour model with 2...

Descripción completa

Detalles Bibliográficos
Autores principales: Hasan, Nurhaslina, Sham, Nur Fatihah Ronny, Karim, Muhammad Khalis Abdul, Fuad, Syed Baharom Syed Ahmad, Hasani, Narimah Abdul Hamid, Omar, Effat, Ibahim, Mohammad Johari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282798/
https://www.ncbi.nlm.nih.gov/pubmed/34267293
http://dx.doi.org/10.1038/s41598-021-93964-5
_version_ 1783723066744897536
author Hasan, Nurhaslina
Sham, Nur Fatihah Ronny
Karim, Muhammad Khalis Abdul
Fuad, Syed Baharom Syed Ahmad
Hasani, Narimah Abdul Hamid
Omar, Effat
Ibahim, Mohammad Johari
author_facet Hasan, Nurhaslina
Sham, Nur Fatihah Ronny
Karim, Muhammad Khalis Abdul
Fuad, Syed Baharom Syed Ahmad
Hasani, Narimah Abdul Hamid
Omar, Effat
Ibahim, Mohammad Johari
author_sort Hasan, Nurhaslina
collection PubMed
description We presented a development of a custom lead shield and mouse strainer for targeted irradiation from the gamma-cell chamber. This study was divided into two parts i.e., to (i) fabricate the shield and strainer from a lead (Pb) and (ii) optimize the irradiation to the mice-bearing tumour model with 2 and 8 Gy absorbed doses. The lead shielding was fabricated into a cuboid shape with a canal on the top and a hole on the vertical side for the beam path. Respective deliveries doses of 28 and 75 Gy from gamma-cell were used to achieve 2 and 8 Gy absorbed doses at the tumour sites.
format Online
Article
Text
id pubmed-8282798
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-82827982021-07-19 Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber Hasan, Nurhaslina Sham, Nur Fatihah Ronny Karim, Muhammad Khalis Abdul Fuad, Syed Baharom Syed Ahmad Hasani, Narimah Abdul Hamid Omar, Effat Ibahim, Mohammad Johari Sci Rep Article We presented a development of a custom lead shield and mouse strainer for targeted irradiation from the gamma-cell chamber. This study was divided into two parts i.e., to (i) fabricate the shield and strainer from a lead (Pb) and (ii) optimize the irradiation to the mice-bearing tumour model with 2 and 8 Gy absorbed doses. The lead shielding was fabricated into a cuboid shape with a canal on the top and a hole on the vertical side for the beam path. Respective deliveries doses of 28 and 75 Gy from gamma-cell were used to achieve 2 and 8 Gy absorbed doses at the tumour sites. Nature Publishing Group UK 2021-07-15 /pmc/articles/PMC8282798/ /pubmed/34267293 http://dx.doi.org/10.1038/s41598-021-93964-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Hasan, Nurhaslina
Sham, Nur Fatihah Ronny
Karim, Muhammad Khalis Abdul
Fuad, Syed Baharom Syed Ahmad
Hasani, Narimah Abdul Hamid
Omar, Effat
Ibahim, Mohammad Johari
Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
title Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
title_full Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
title_fullStr Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
title_full_unstemmed Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
title_short Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
title_sort development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282798/
https://www.ncbi.nlm.nih.gov/pubmed/34267293
http://dx.doi.org/10.1038/s41598-021-93964-5
work_keys_str_mv AT hasannurhaslina developmentofcustomleadshieldandstrainerfortargetedirradiationformiceinthegammacellchamber
AT shamnurfatihahronny developmentofcustomleadshieldandstrainerfortargetedirradiationformiceinthegammacellchamber
AT karimmuhammadkhalisabdul developmentofcustomleadshieldandstrainerfortargetedirradiationformiceinthegammacellchamber
AT fuadsyedbaharomsyedahmad developmentofcustomleadshieldandstrainerfortargetedirradiationformiceinthegammacellchamber
AT hasaninarimahabdulhamid developmentofcustomleadshieldandstrainerfortargetedirradiationformiceinthegammacellchamber
AT omareffat developmentofcustomleadshieldandstrainerfortargetedirradiationformiceinthegammacellchamber
AT ibahimmohammadjohari developmentofcustomleadshieldandstrainerfortargetedirradiationformiceinthegammacellchamber

Ejemplares similares