Non-flipping DNA glycosylase AlkD scans DNA without formation of a stable interrogation complex

The multi-step base excision repair (BER) pathway is initiated by a set of enzymes, known as DNA glycosylases, able to scan DNA and detect modified bases among a vast number of normal bases. While DNA glycosylases in the BER pathway generally bend the DNA and flip damaged bases into lesion specific...

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Detalles Bibliográficos
Autores principales: Ahmadi, Arash, Till, Katharina, Backe, Paul Hoff, Blicher, Pernille, Diekmann, Robin, Schüttpelz, Mark, Glette, Kyrre, Tørresen, Jim, Bjørås, Magnar, Rowe, Alexander D., Dalhus, Bjørn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282808/
https://www.ncbi.nlm.nih.gov/pubmed/34267321
http://dx.doi.org/10.1038/s42003-021-02400-x

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