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Comparative Effect of 22 Dietary Sources of Fiber on Gut Microbiota of Healthy Humans in vitro

Human gut microbiota has a fundamental role in human health, and diet is one of the most relevant factors modulating the gut microbial ecosystem. Fiber, fat, proteins, and micronutrients can shape microbial activity and structure. Much information is available on the role of defined prebiotic fibers...

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Autores principales: Calatayud, Marta, Van den Abbeele, Pieter, Ghyselinck, Jonas, Marzorati, Massimo, Rohs, Eric, Birkett, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282825/
https://www.ncbi.nlm.nih.gov/pubmed/34277691
http://dx.doi.org/10.3389/fnut.2021.700571
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author Calatayud, Marta
Van den Abbeele, Pieter
Ghyselinck, Jonas
Marzorati, Massimo
Rohs, Eric
Birkett, Anne
author_facet Calatayud, Marta
Van den Abbeele, Pieter
Ghyselinck, Jonas
Marzorati, Massimo
Rohs, Eric
Birkett, Anne
author_sort Calatayud, Marta
collection PubMed
description Human gut microbiota has a fundamental role in human health, and diet is one of the most relevant factors modulating the gut microbial ecosystem. Fiber, fat, proteins, and micronutrients can shape microbial activity and structure. Much information is available on the role of defined prebiotic fibers on gut microbiota, but less known are the effects of intact dietary fiber sources on healthy gut ecosystems. This research investigated in vitro the short-term effect of 22 commercially available food sources of dietary fiber on gut microbiota activity [pH, gas, short-chain fatty acids (SCFA), branched fatty acids (BCFA), lactate] and specific composition of Firmicutes, Bacteroidetes, bifidobacteria, and lactobacilli populations. More than 80% (19 of 22) of the products were highly fermentable and induced SCFAs production, with specific product differences. In general, all the whole grain cereals had a similar effect on gut microbiota modulation, inducing acetate and butyrate production and increasing bifidobacteria levels. Incorporating and comparing a large variety of products, including “non-conventional” fiber sources, like konjac, bamboo fiber, or seeds fiber, about which there is little information, contributes to our knowledge on the modulatory activity of diverse food fiber sources on human gut microbiota, and therefore potential health promotion through dietary fiber diversification.
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spelling pubmed-82828252021-07-17 Comparative Effect of 22 Dietary Sources of Fiber on Gut Microbiota of Healthy Humans in vitro Calatayud, Marta Van den Abbeele, Pieter Ghyselinck, Jonas Marzorati, Massimo Rohs, Eric Birkett, Anne Front Nutr Nutrition Human gut microbiota has a fundamental role in human health, and diet is one of the most relevant factors modulating the gut microbial ecosystem. Fiber, fat, proteins, and micronutrients can shape microbial activity and structure. Much information is available on the role of defined prebiotic fibers on gut microbiota, but less known are the effects of intact dietary fiber sources on healthy gut ecosystems. This research investigated in vitro the short-term effect of 22 commercially available food sources of dietary fiber on gut microbiota activity [pH, gas, short-chain fatty acids (SCFA), branched fatty acids (BCFA), lactate] and specific composition of Firmicutes, Bacteroidetes, bifidobacteria, and lactobacilli populations. More than 80% (19 of 22) of the products were highly fermentable and induced SCFAs production, with specific product differences. In general, all the whole grain cereals had a similar effect on gut microbiota modulation, inducing acetate and butyrate production and increasing bifidobacteria levels. Incorporating and comparing a large variety of products, including “non-conventional” fiber sources, like konjac, bamboo fiber, or seeds fiber, about which there is little information, contributes to our knowledge on the modulatory activity of diverse food fiber sources on human gut microbiota, and therefore potential health promotion through dietary fiber diversification. Frontiers Media S.A. 2021-07-02 /pmc/articles/PMC8282825/ /pubmed/34277691 http://dx.doi.org/10.3389/fnut.2021.700571 Text en Copyright © 2021 Calatayud, Van den Abbeele, Ghyselinck, Marzorati, Rohs and Birkett. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Calatayud, Marta
Van den Abbeele, Pieter
Ghyselinck, Jonas
Marzorati, Massimo
Rohs, Eric
Birkett, Anne
Comparative Effect of 22 Dietary Sources of Fiber on Gut Microbiota of Healthy Humans in vitro
title Comparative Effect of 22 Dietary Sources of Fiber on Gut Microbiota of Healthy Humans in vitro
title_full Comparative Effect of 22 Dietary Sources of Fiber on Gut Microbiota of Healthy Humans in vitro
title_fullStr Comparative Effect of 22 Dietary Sources of Fiber on Gut Microbiota of Healthy Humans in vitro
title_full_unstemmed Comparative Effect of 22 Dietary Sources of Fiber on Gut Microbiota of Healthy Humans in vitro
title_short Comparative Effect of 22 Dietary Sources of Fiber on Gut Microbiota of Healthy Humans in vitro
title_sort comparative effect of 22 dietary sources of fiber on gut microbiota of healthy humans in vitro
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282825/
https://www.ncbi.nlm.nih.gov/pubmed/34277691
http://dx.doi.org/10.3389/fnut.2021.700571
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