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Extensive transcriptional and chromatin changes underlie astrocyte maturation in vivo and in culture
Astrocytes have essential functions in brain homeostasis that are established late in differentiation, but the mechanisms underlying the functional maturation of astrocytes are not well understood. Here we identify extensive transcriptional changes that occur during murine astrocyte maturation in vi...
Autores principales: | Lattke, Michael, Goldstone, Robert, Ellis, James K., Boeing, Stefan, Jurado-Arjona, Jerónimo, Marichal, Nicolás, MacRae, James I., Berninger, Benedikt, Guillemot, Francois |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282848/ https://www.ncbi.nlm.nih.gov/pubmed/34267208 http://dx.doi.org/10.1038/s41467-021-24624-5 |
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