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A new approach to produce [(18)F]MC225 via one-step synthesis, a PET radiotracer for measuring P-gp function

BACKGROUND: [(18)F]MC225 is a radiotracer for imaging P-glycoprotein (P-gp) function at the blood-brain barrier. The P-gp function can be altered due to different factors, for instance, decreased P-gp function has been described in patients with Alzheimer’s or Parkinson’s Disease. The current applie...

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Detalles Bibliográficos
Autores principales:	Garcia-Varela, Lara, Attia, Khaled, Sembrano, John Carlo, Jacquet, Olivier, Antunes, Inês F., Kwizera, Chantal, Visser, Ton J., Dierckx, Rudi A. J. O., Elsinga, Philip H., Luurtsema, Gert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282851/ https://www.ncbi.nlm.nih.gov/pubmed/34264435 http://dx.doi.org/10.1186/s41181-021-00139-8

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