Cargando…

Selectively targeting haemagglutinin antigen to chicken CD83 receptor induces faster and stronger immunity against avian influenza

The immunogenicity and protective efficacy of vaccines can be enhanced by the selective delivery of antigens to the antigen-presenting cells (APCs). In this study, H9N2 avian influenza virus haemagglutinin (HA) antigen, was targeted by fusing it to single-chain fragment variable (scFv) antibodies sp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shrestha, Angita, Sadeyen, Jean-Remy, Lukosaityte, Deimante, Chang, Pengxiang, Smith, Adrian, Van Hulten, Marielle, Iqbal, Munir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282863/ https://www.ncbi.nlm.nih.gov/pubmed/34267228 http://dx.doi.org/10.1038/s41541-021-00350-3

Ejemplares similares

Author Correction: Selectively targeting haemagglutinin antigen to chicken CD83 receptor induces faster and stronger immunity against avian influenza
por: Shrestha, Angita, et al.
Publicado: (2022)

Targeting Haemagglutinin Antigen of Avian Influenza Virus to Chicken Immune Cell Receptors Dec205 and CD11c Induces Differential Immune-Potentiating Responses
por: Shrestha, Angita, et al.
Publicado: (2021)

Haemagglutinin antigen selectively targeted to chicken CD83 overcomes interference from maternally derived antibodies in chickens
por: Shrestha, Angita, et al.
Publicado: (2022)

Engineered Recombinant Single Chain Variable Fragment of Monoclonal Antibody Provides Protection to Chickens Infected with H9N2 Avian Influenza
por: Lukosaityte, Deimante, et al.
Publicado: (2020)

Immune Escape Adaptive Mutations in the H7N9 Avian Influenza Hemagglutinin Protein Increase Virus Replication Fitness and Decrease Pandemic Potential
por: Chang, Pengxiang, et al.
Publicado: (2020)

Characterization of the haemagglutinin properties of the H5N1 avian influenza virus that caused human infections in Cambodia
por: Chang, Pengxiang, et al.
Publicado: (2023)

Enhancing Protective Efficacy of Poultry Vaccines through Targeted Delivery of Antigens to Antigen-Presenting Cells
por: Shrestha, Angita, et al.
Publicado: (2018)

Antigenic Characterization of Human Monoclonal Antibodies for Therapeutic Use against H7N9 Avian Influenza Virus
por: Chang, Pengxiang, et al.
Publicado: (2022)

Amino Acid Residue 217 in the Hemagglutinin Glycoprotein Is a Key Mediator of Avian Influenza H7N9 Virus Antigenicity
por: Chang, Pengxiang, et al.
Publicado: (2018)

Variability in H9N2 haemagglutinin receptor-binding preference and the pH of fusion
por: Peacock, Thomas P, et al.
Publicado: (2017)

Risk assessment of the newly emerged H7N9 avian influenza viruses
por: Chang, Pengxiang, et al.
Publicado: (2023)

The molecular basis of antigenic variation among A(H9N2) avian influenza viruses
por: Peacock, Thomas P., et al.
Publicado: (2018)

Application of HDR-CRISPR/Cas9 and Erythrocyte Binding for Rapid Generation of Recombinant Turkey Herpesvirus-Vectored Avian Influenza Virus Vaccines
por: Chang, Pengxiang, et al.
Publicado: (2019)

Presence of Antibodies to SARS-CoV-2 in Domestic Cats in Istanbul, Turkey, Before and After COVID-19 Pandemic
por: Yilmaz, Aysun, et al.
Publicado: (2021)

The Application of NHEJ-CRISPR/Cas9 and Cre-Lox System in the Generation of Bivalent Duck Enteritis Virus Vaccine against Avian Influenza Virus
por: Chang, Pengxiang, et al.
Publicado: (2018)

Adsorptive mutation and N-linked glycosylation modulate influenza virus antigenicity and fitness
por: Sealy, Joshua E., et al.
Publicado: (2020)

Current and Novel Approaches in Influenza Management
por: Kotey, Erasmus, et al.
Publicado: (2019)

Evolutionary interactions between haemagglutinin and neuraminidase in avian influenza
por: Ward, Melissa J, et al.
Publicado: (2013)

LDpred2: better, faster, stronger
por: Privé, Florian, et al.
Publicado: (2020)

Poultry trading behaviours in Vietnamese live bird markets as risk factors for avian influenza infection in chickens
por: Sealy, Joshua E., et al.
Publicado: (2019)

Amino acid substitutions in the H5N1 avian influenza haemagglutinin alter pH of fusion and receptor binding to promote a highly pathogenic phenotype in chickens
por: Sealy, Joshua E., et al.
Publicado: (2021)

A ligation and restriction enzyme independent cloning technique: an alternative to conventional methods for cloning hard-to-clone gene segments in the influenza reverse genetics system
por: Bhat, Sushant, et al.
Publicado: (2020)

Electrostatic Variation of Haemagglutinin as a Hallmark of the Evolution of Avian Influenza Viruses
por: Heidari, Alireza, et al.
Publicado: (2018)

PA-X is an avian virulence factor in H9N2 avian influenza virus
por: Clements, Anabel L., et al.
Publicado: (2021)

Immune Response in Mice Immunized with Chimeric H1 Antigens
por: Kotey, Erasmus Nikoi, et al.
Publicado: (2021)

The Origin of Internal Genes Contributes to the Replication and Transmission Fitness of H7N9 Avian Influenza Virus
por: James, Joe, et al.
Publicado: (2022)

Mobile-surface bubbles and droplets coalesce faster but bounce stronger
por: Vakarelski, Ivan U., et al.
Publicado: (2019)

Coinfection of Chickens with H9N2 and H7N9 Avian Influenza Viruses Leads to Emergence of Reassortant H9N9 Virus with Increased Fitness for Poultry and a Zoonotic Potential
por: Bhat, Sushant, et al.
Publicado: (2022)

The Vestigial Esterase Domain of Haemagglutinin of H5N1 Avian Influenza A Virus: Antigenicity and Contribution to Viral Pathogenesis
por: Zheng, Zhiqiang, et al.
Publicado: (2018)

Evolution of high pathogenicity of H5 avian influenza virus: haemagglutinin cleavage site selection of reverse-genetics mutants during passage in chickens
por: Luczo, Jasmina M., et al.
Publicado: (2018)

Bigger, faster, stronger: stepping up the hunt for cosmic building blocks
por: McKie, Robin
Publicado: (2013)

Global clinical trial mobilization for COVID-19: higher, faster, stronger
por: Beall, Reed F., et al.
Publicado: (2020)

Harder, better, faster, stronger: Colistin resistance mechanisms in Escherichia coli
por: Janssen, Axel B., et al.
Publicado: (2021)

Exercise Intensity and Coronary Plaque Composition: Is Harder, Better, Faster, Stronger?
por: Guseh, J. Sawalla, et al.
Publicado: (2022)

Contribution of Segment 3 to the Acquisition of Virulence in Contemporary H9N2 Avian Influenza Viruses
por: Clements, Anabel L., et al.
Publicado: (2020)

Motivational goal-priming with or without awareness produces faster and stronger force exertion
por: Takarada, Yudai, et al.
Publicado: (2018)

Greener, Faster, Stronger: The Benefits of Deep Eutectic Solvents in Polymer and Materials Science
por: Nahar, Yeasmin, et al.
Publicado: (2021)

Mapping of three antigenic sites on the haemagglutinin-neuraminidase protein of Newcastle disease virus
por: Yusoff, Khatijah, et al.
Publicado: (1988)

Molecular pathogenesis of H5 highly pathogenic avian influenza: the role of the haemagglutinin cleavage site motif
por: Luczo, Jasmina M., et al.
Publicado: (2015)

Rapid, in-field deployable, avian influenza virus haemagglutinin characterisation tool using MinION technology
por: de Vries, Ellen M., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_kiitpmd236b1844sl3ne52picl