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Comparison of the Filtration Efficiency of Different Face Masks Against Aerosols

Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic can spread through virus-containing aerosols ( ≤ 5 μm) and larger airborne droplets. Quantifying filtration efficiency of different kinds of masks and linings for aerosols that fall within the most penetrating part...

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Autores principales: Stahl, Connor, Frederick, Kevin, Chaudhary, Sachin, Morton, Christopher J., Loy, Douglas, Muralidharan, Krishna, Sorooshian, Armin, Parthasarathy, Sairam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282900/
https://www.ncbi.nlm.nih.gov/pubmed/34277652
http://dx.doi.org/10.3389/fmed.2021.654317
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author Stahl, Connor
Frederick, Kevin
Chaudhary, Sachin
Morton, Christopher J.
Loy, Douglas
Muralidharan, Krishna
Sorooshian, Armin
Parthasarathy, Sairam
author_facet Stahl, Connor
Frederick, Kevin
Chaudhary, Sachin
Morton, Christopher J.
Loy, Douglas
Muralidharan, Krishna
Sorooshian, Armin
Parthasarathy, Sairam
author_sort Stahl, Connor
collection PubMed
description Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic can spread through virus-containing aerosols ( ≤ 5 μm) and larger airborne droplets. Quantifying filtration efficiency of different kinds of masks and linings for aerosols that fall within the most penetrating particle size (80-400 nm) is critical to limiting viral transmission. The objective of our experiment was to compare the “real-world” filtering efficiency of different face masks for fine aerosols (350 nm) in laboratory simulations. Methods: We performed a simulated bench test that measured the filtering efficiency of N95 vs. N99 masks with elastomeric lining in relation to baseline (“background”) aerosol generation. A mannequin head was placed within a chamber and was attached to an artificial lung simulator. Particles of known size (350 ± 6 nm aerodynamic diameter) were aerosolized into the chamber while simulating breathing at physiological settings of tidal volume, respiratory rate, and airflow. Particle counts were measured between the mannequin head and the lung simulator at the tracheal airway location. Results: Baseline particle counts without a filter (background) were 2,935 ± 555 (SD) cm(−3), while the N95 (1348 ± 92 cm(−3)) and N99 mask with elastomeric lining (279 ± 164 cm(−3); p <0.0001) exhibit lower counts due to filtration. Conclusion: The filtration efficiency of the N95 (54.1%) and N99 (90.5%) masks were lower than the filtration efficiency rating. N99 masks with elastomeric lining exhibit greater filtration efficiency than N95 masks without elastomeric lining and may be preferred to contain the spread of SARS-CoV-2 infection.
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spelling pubmed-82829002021-07-17 Comparison of the Filtration Efficiency of Different Face Masks Against Aerosols Stahl, Connor Frederick, Kevin Chaudhary, Sachin Morton, Christopher J. Loy, Douglas Muralidharan, Krishna Sorooshian, Armin Parthasarathy, Sairam Front Med (Lausanne) Medicine Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic can spread through virus-containing aerosols ( ≤ 5 μm) and larger airborne droplets. Quantifying filtration efficiency of different kinds of masks and linings for aerosols that fall within the most penetrating particle size (80-400 nm) is critical to limiting viral transmission. The objective of our experiment was to compare the “real-world” filtering efficiency of different face masks for fine aerosols (350 nm) in laboratory simulations. Methods: We performed a simulated bench test that measured the filtering efficiency of N95 vs. N99 masks with elastomeric lining in relation to baseline (“background”) aerosol generation. A mannequin head was placed within a chamber and was attached to an artificial lung simulator. Particles of known size (350 ± 6 nm aerodynamic diameter) were aerosolized into the chamber while simulating breathing at physiological settings of tidal volume, respiratory rate, and airflow. Particle counts were measured between the mannequin head and the lung simulator at the tracheal airway location. Results: Baseline particle counts without a filter (background) were 2,935 ± 555 (SD) cm(−3), while the N95 (1348 ± 92 cm(−3)) and N99 mask with elastomeric lining (279 ± 164 cm(−3); p <0.0001) exhibit lower counts due to filtration. Conclusion: The filtration efficiency of the N95 (54.1%) and N99 (90.5%) masks were lower than the filtration efficiency rating. N99 masks with elastomeric lining exhibit greater filtration efficiency than N95 masks without elastomeric lining and may be preferred to contain the spread of SARS-CoV-2 infection. Frontiers Media S.A. 2021-07-02 /pmc/articles/PMC8282900/ /pubmed/34277652 http://dx.doi.org/10.3389/fmed.2021.654317 Text en Copyright © 2021 Stahl, Frederick, Chaudhary, Morton, Loy, Muralidharan, Sorooshian and Parthasarathy. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Stahl, Connor
Frederick, Kevin
Chaudhary, Sachin
Morton, Christopher J.
Loy, Douglas
Muralidharan, Krishna
Sorooshian, Armin
Parthasarathy, Sairam
Comparison of the Filtration Efficiency of Different Face Masks Against Aerosols
title Comparison of the Filtration Efficiency of Different Face Masks Against Aerosols
title_full Comparison of the Filtration Efficiency of Different Face Masks Against Aerosols
title_fullStr Comparison of the Filtration Efficiency of Different Face Masks Against Aerosols
title_full_unstemmed Comparison of the Filtration Efficiency of Different Face Masks Against Aerosols
title_short Comparison of the Filtration Efficiency of Different Face Masks Against Aerosols
title_sort comparison of the filtration efficiency of different face masks against aerosols
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282900/
https://www.ncbi.nlm.nih.gov/pubmed/34277652
http://dx.doi.org/10.3389/fmed.2021.654317
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