Doxorubicin induces dysregulation of AMPA receptor and impairs hippocampal synaptic plasticity leading to learning and memory deficits

Doxorubicin (Dox) is a chemotherapeutic agent used widely to treat a variety of malignant cancers. However, Dox chemotherapy is associated with several adverse effects, including “chemobrain,” the observation that cancer patients exhibit through learning and memory difficulties extending even beyond...

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Detalles Bibliográficos
Autores principales: Alhowail, Ahmad H., Pinky, Priyanka D., Eggert, Matthew, Bloemer, Jenna, Woodie, Lauren N., Buabeid, Manal A., Bhattacharya, Subhrajit, Jasper, Shanese L., Bhattacharya, Dwipayan, Dhanasekaran, Muralikrishnan, Escobar, Martha, Arnold, Robert D., Suppiramaniam, Vishnu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282984/
https://www.ncbi.nlm.nih.gov/pubmed/34296005
http://dx.doi.org/10.1016/j.heliyon.2021.e07456

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