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Trimethylacetic Anhydride–Based Derivatization Facilitates Quantification of Histone Marks at the MS1 Level

Histone post-translational modifications (hPTMs) are epigenetic marks that strongly affect numerous processes, including cell cycling and protein interactions. They have been studied by both antibody- and MS-based methods for years, but the analyses are still challenging, mainly because of the diver...

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Detalles Bibliográficos
Autores principales: Kuchaříková, Hana, Dobrovolná, Pavlína, Lochmanová, Gabriela, Zdráhal, Zbyněk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283018/
https://www.ncbi.nlm.nih.gov/pubmed/34129942
http://dx.doi.org/10.1016/j.mcpro.2021.100114

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