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Presumed cytomegalovirus retinitis in a non-immune compromised patient with breast carcinoma during treatment: A case report

PURPOSE: Cytomegalovirus (CMV) retinitis is one of the most common opportunistic infections in immunocompromised patients, including patients with acquired immunodeficiency syndrome (AIDS). CMV retinitis in non-human immunodeficiency virus (HIV)-infected patients has been reported with variable pres...

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Detalles Bibliográficos
Autores principales: Kao, Chia-Chen, Hsu, Shiuh-Liang, Sheu, Shwu-Jiuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283142/
https://www.ncbi.nlm.nih.gov/pubmed/34307962
http://dx.doi.org/10.1016/j.ajoc.2021.101161
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author Kao, Chia-Chen
Hsu, Shiuh-Liang
Sheu, Shwu-Jiuan
author_facet Kao, Chia-Chen
Hsu, Shiuh-Liang
Sheu, Shwu-Jiuan
author_sort Kao, Chia-Chen
collection PubMed
description PURPOSE: Cytomegalovirus (CMV) retinitis is one of the most common opportunistic infections in immunocompromised patients, including patients with acquired immunodeficiency syndrome (AIDS). CMV retinitis in non-human immunodeficiency virus (HIV)-infected patients has been reported with variable presentations. Significant intraocular inflammation is common, and visual prognosis is poor if not properly managed. OBSERVATIONS: We present a case of presumed CMV retinitis in a non-immunocompromised breast cancer patient that occurred during cancer treatment. The ocular symptoms developed one day after partial mastectomy with intra-operative radiotherapy following five months of chemotherapy treatment. Ocular manifestations included panuveitis with mild peripheral retinitis. CONCLUSIONS AND IMPORTANCE: Early diagnosis and prompt treatment with oral valganciclovir based on the clinical manifestation and serologic test findings helped to preserve vision.
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spelling pubmed-82831422021-07-22 Presumed cytomegalovirus retinitis in a non-immune compromised patient with breast carcinoma during treatment: A case report Kao, Chia-Chen Hsu, Shiuh-Liang Sheu, Shwu-Jiuan Am J Ophthalmol Case Rep Case Report PURPOSE: Cytomegalovirus (CMV) retinitis is one of the most common opportunistic infections in immunocompromised patients, including patients with acquired immunodeficiency syndrome (AIDS). CMV retinitis in non-human immunodeficiency virus (HIV)-infected patients has been reported with variable presentations. Significant intraocular inflammation is common, and visual prognosis is poor if not properly managed. OBSERVATIONS: We present a case of presumed CMV retinitis in a non-immunocompromised breast cancer patient that occurred during cancer treatment. The ocular symptoms developed one day after partial mastectomy with intra-operative radiotherapy following five months of chemotherapy treatment. Ocular manifestations included panuveitis with mild peripheral retinitis. CONCLUSIONS AND IMPORTANCE: Early diagnosis and prompt treatment with oral valganciclovir based on the clinical manifestation and serologic test findings helped to preserve vision. Elsevier 2021-07-07 /pmc/articles/PMC8283142/ /pubmed/34307962 http://dx.doi.org/10.1016/j.ajoc.2021.101161 Text en © 2021 Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kao, Chia-Chen
Hsu, Shiuh-Liang
Sheu, Shwu-Jiuan
Presumed cytomegalovirus retinitis in a non-immune compromised patient with breast carcinoma during treatment: A case report
title Presumed cytomegalovirus retinitis in a non-immune compromised patient with breast carcinoma during treatment: A case report
title_full Presumed cytomegalovirus retinitis in a non-immune compromised patient with breast carcinoma during treatment: A case report
title_fullStr Presumed cytomegalovirus retinitis in a non-immune compromised patient with breast carcinoma during treatment: A case report
title_full_unstemmed Presumed cytomegalovirus retinitis in a non-immune compromised patient with breast carcinoma during treatment: A case report
title_short Presumed cytomegalovirus retinitis in a non-immune compromised patient with breast carcinoma during treatment: A case report
title_sort presumed cytomegalovirus retinitis in a non-immune compromised patient with breast carcinoma during treatment: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283142/
https://www.ncbi.nlm.nih.gov/pubmed/34307962
http://dx.doi.org/10.1016/j.ajoc.2021.101161
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