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Microglia replacement by microglia transplantation (Mr MT) in the adult mouse brain

Mutations in microglia may cause brain disorders. Replacement of dysfunctional microglia by allogeneic wild-type microglia from bone marrow transplantation (Mr BMT) or peripheral blood can correct the gene deficiency at the brain-wide scale but cannot achieve precise replacement at specific brain re...

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Detalles Bibliográficos
Autores principales: Xu, Zhen, Peng, Bo, Rao, Yanxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283144/
https://www.ncbi.nlm.nih.gov/pubmed/34308380
http://dx.doi.org/10.1016/j.xpro.2021.100665