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Microglia replacement by microglia transplantation (Mr MT) in the adult mouse brain
Mutations in microglia may cause brain disorders. Replacement of dysfunctional microglia by allogeneic wild-type microglia from bone marrow transplantation (Mr BMT) or peripheral blood can correct the gene deficiency at the brain-wide scale but cannot achieve precise replacement at specific brain re...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283144/ https://www.ncbi.nlm.nih.gov/pubmed/34308380 http://dx.doi.org/10.1016/j.xpro.2021.100665 |