Cargando…
Synaptic density in carriers of C9orf72 mutations: a [(11)C]UCB‐J PET study
Synaptic loss is an early and clinically relevant feature of many neurodegenerative diseases. Here we assess three adults at risk of frontotemporal dementia from C9orf72 mutation, using [(11)C]UCB‐J PET to quantify synaptic density in comparison with 19 healthy controls and one symptomatic patient w...
Autores principales: | Malpetti, Maura, Holland, Negin, Jones, P. Simon, Ye, Rong, Cope, Thomas E., Fryer, Tim D., Hong, Young T., Savulich, George, Rittman, Timothy, Passamonti, Luca, Mak, Elijah, Aigbirhio, Franklin I., O’Brien, John T., Rowe, James B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283163/ https://www.ncbi.nlm.nih.gov/pubmed/34133849 http://dx.doi.org/10.1002/acn3.51407 |
Ejemplares similares
-
Molecular pathology and synaptic loss in primary tauopathies: an (18)F-AV-1451 and (11)C-UCB-J PET study
por: Holland, Negin, et al.
Publicado: (2021) -
Synaptic Loss in Frontotemporal Dementia Revealed by [
(11)C]UCB‐J Positron Emission Tomography
por: Malpetti, Maura, et al.
Publicado: (2022) -
(11)C-UCB-J synaptic PET and multimodal imaging in dementia with Lewy bodies
por: Nicastro, Nicolas, et al.
Publicado: (2020) -
In vivo coupling of dendritic complexity with presynaptic density in primary tauopathies
por: Mak, Elijah, et al.
Publicado: (2021) -
[(18)F]AV‐1451 binding is increased in frontotemporal dementia due to C9orf72 expansion
por: Bevan‐Jones, Richard W., et al.
Publicado: (2018)