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Novel Dent disease 1 cellular models reveal biological processes underlying ClC-5 loss-of-function

Dent disease 1 (DD1) is a rare X-linked renal proximal tubulopathy characterized by low molecular weight proteinuria and variable degree of hypercalciuria, nephrocalcinosis and/or nephrolithiasis, progressing to chronic kidney disease. Although mutations in the electrogenic Cl(−)/H(+) antiporter ClC...

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Detalles Bibliográficos
Autores principales:	Durán, Mónica, Burballa, Carla, Cantero-Recasens, Gerard, Butnaru, Cristian M, Malhotra, Vivek, Ariceta, Gema, Sarró, Eduard, Meseguer, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	General Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283206/ https://www.ncbi.nlm.nih.gov/pubmed/33987651 http://dx.doi.org/10.1093/hmg/ddab131

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