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Celsr3 is required for Purkinje cell maturation and regulates cerebellar postsynaptic plasticity

Atypical cadherin Celsr3 is critical for brain embryonic development, and its role in the postnatal cerebellum remains unknown. Using Celsr3-GFP mice, Celsr3 shows high expression in postnatal Purkinje cells (PCs). Mice with conditional knockout (cKO) of Celsr3 in postnatal PCs exhibit deficit in mo...

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Detalles Bibliográficos
Autores principales:	Zhou, Qinji, Qin, Jingwen, Liang, Yaying, Zhang, Wei, He, Siyuan, Tissir, Fadel, Qu, Yibo, Zhou, Libing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283331/ https://www.ncbi.nlm.nih.gov/pubmed/34308297 http://dx.doi.org/10.1016/j.isci.2021.102812

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