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A Chondroitin Sulfate Chain of Urinary Trypsin Inhibitor Enhances Protease Inhibitory Activity of the Core Protein

Human urinary trypsin inhibitor (UTI) is a proteoglycan composed of one core protein covalently linked to one glycosaminoglycan, which is a low sulfated chondroitin 4-sulfate. It is used as an anti-inflammatory medicine based on the protease inhibitory activity of the core protein. However, function...

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Detalles Bibliográficos
Autores principales: Teshigahara, Yu, Kakizaki, Ikuko, Hirao, Wataru, Tanaka, Kanji, Takahashi, Ryoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Applied Glycoscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283410/
https://www.ncbi.nlm.nih.gov/pubmed/34354530
http://dx.doi.org/10.5458/jag.jag.JAG-2019_0021

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