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Safety and Preliminary Efficacy of Lorcaserin for Cocaine Use Disorder: A Phase I Randomized Clinical Trial

Background and Objectives: Preclinical studies show serotonin (5-HT) 5-HT(2C) receptor (5-HT(2C)R) agonists reduce cocaine-seeking and cocaine intake. This study examined safety of the 5-HT(2C)R agonist lorcaserin administered with cocaine in participants with cocaine use disorder (CocUD). Secondari...

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Detalles Bibliográficos
Autores principales:	Johns, Sade E., Keyser-Marcus, Lori, Abbate, Antonio, Boone, Edward, Van Tassell, Benjamin, Cunningham, Kathryn A., Anastasio, Noelle C., Poklis, Justin L., Ramey, Tatiana, Moeller, F. Gerard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Psychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283411/ https://www.ncbi.nlm.nih.gov/pubmed/34276440 http://dx.doi.org/10.3389/fpsyt.2021.666945

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