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The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19
BACKGROUND/AIM: It is very important for the efficient use of limited capacity and the success of treatment to predict patients who may need ICU with high mortality rate in the Covid-19 outbreak. In our study, it was aimed to investigate the value of the radiological involvement on initial CT in dem...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Scientific and Technological Research Council of Turkey
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283482/ https://www.ncbi.nlm.nih.gov/pubmed/33705639 http://dx.doi.org/10.3906/sag-2009-49 |
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author | AYDEMİR, Yusuf GÜNDÜZ, Yasemin KÖROĞLU, Mehmet KARABAY, Oğuz DHEİR, Hamad ŞENGÜL, Aysun YAYLACI, Selçuk KOCAYİĞİT, Havva ERDEM, Ali Fuat AYDEMİR, Özlem GÜÇLÜ, Ertuğrul YÜRÜMEZ, Yusuf |
author_facet | AYDEMİR, Yusuf GÜNDÜZ, Yasemin KÖROĞLU, Mehmet KARABAY, Oğuz DHEİR, Hamad ŞENGÜL, Aysun YAYLACI, Selçuk KOCAYİĞİT, Havva ERDEM, Ali Fuat AYDEMİR, Özlem GÜÇLÜ, Ertuğrul YÜRÜMEZ, Yusuf |
author_sort | AYDEMİR, Yusuf |
collection | PubMed |
description | BACKGROUND/AIM: It is very important for the efficient use of limited capacity and the success of treatment to predict patients who may need ICU with high mortality rate in the Covid-19 outbreak. In our study, it was aimed to investigate the value of the radiological involvement on initial CT in demonstrating the ICU transfer and mortality rate of patients. MATERIALS AND METHODS: All PCR-positive patients were included in the study, whose CT, PCR, and laboratory values were obtained simultaneously at the time of first admission. Patients were divided into 4 groups in terms of the extent of radiological lesions. These groups were compared in terms of intensive care transfer needs and Covid-related mortality rates. RESULTS: A total of 477 patients were included in the study. Ninety of them were group 0 (no lung involvement), 162 were group 1 (mild lesion), 89 were group 2 (moderate lesion), and 136 were group 3 (severe lung involvement). A significant relationship was found between the extensiveness of the radiological lesion on CT and admission to intensive care and mortality rate. As the initial radiological involvement amounts increased, the rate of ICU transfer and mortality increased. The mortality rates of the groups were 0%, 3%, 12.3%, and 12.5%, respectively, and the difference was significant (p < 0.001). Similarly, the ICU transfer rates of the groups were 2.2%, 5.6%, 13.5%, and 17.7%, respectively, and the difference was significant (p < 0.001). CONCLUSION: In conclusion, in our study, the strong relationship between the initial radiological extent assessment and the need for intensive care and mortality rates has been demonstrated, and we believe that our results will make a significant contribution to increase the success of the health system in predicting patients who may progress, helping clinicians and managing pandemics. |
format | Online Article Text |
id | pubmed-8283482 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Scientific and Technological Research Council of Turkey |
record_format | MEDLINE/PubMed |
spelling | pubmed-82834822021-08-02 The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19 AYDEMİR, Yusuf GÜNDÜZ, Yasemin KÖROĞLU, Mehmet KARABAY, Oğuz DHEİR, Hamad ŞENGÜL, Aysun YAYLACI, Selçuk KOCAYİĞİT, Havva ERDEM, Ali Fuat AYDEMİR, Özlem GÜÇLÜ, Ertuğrul YÜRÜMEZ, Yusuf Turk J Med Sci Article BACKGROUND/AIM: It is very important for the efficient use of limited capacity and the success of treatment to predict patients who may need ICU with high mortality rate in the Covid-19 outbreak. In our study, it was aimed to investigate the value of the radiological involvement on initial CT in demonstrating the ICU transfer and mortality rate of patients. MATERIALS AND METHODS: All PCR-positive patients were included in the study, whose CT, PCR, and laboratory values were obtained simultaneously at the time of first admission. Patients were divided into 4 groups in terms of the extent of radiological lesions. These groups were compared in terms of intensive care transfer needs and Covid-related mortality rates. RESULTS: A total of 477 patients were included in the study. Ninety of them were group 0 (no lung involvement), 162 were group 1 (mild lesion), 89 were group 2 (moderate lesion), and 136 were group 3 (severe lung involvement). A significant relationship was found between the extensiveness of the radiological lesion on CT and admission to intensive care and mortality rate. As the initial radiological involvement amounts increased, the rate of ICU transfer and mortality increased. The mortality rates of the groups were 0%, 3%, 12.3%, and 12.5%, respectively, and the difference was significant (p < 0.001). Similarly, the ICU transfer rates of the groups were 2.2%, 5.6%, 13.5%, and 17.7%, respectively, and the difference was significant (p < 0.001). CONCLUSION: In conclusion, in our study, the strong relationship between the initial radiological extent assessment and the need for intensive care and mortality rates has been demonstrated, and we believe that our results will make a significant contribution to increase the success of the health system in predicting patients who may progress, helping clinicians and managing pandemics. The Scientific and Technological Research Council of Turkey 2021-06-28 /pmc/articles/PMC8283482/ /pubmed/33705639 http://dx.doi.org/10.3906/sag-2009-49 Text en Copyright © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Article AYDEMİR, Yusuf GÜNDÜZ, Yasemin KÖROĞLU, Mehmet KARABAY, Oğuz DHEİR, Hamad ŞENGÜL, Aysun YAYLACI, Selçuk KOCAYİĞİT, Havva ERDEM, Ali Fuat AYDEMİR, Özlem GÜÇLÜ, Ertuğrul YÜRÜMEZ, Yusuf The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19 |
title | The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19 |
title_full | The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19 |
title_fullStr | The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19 |
title_full_unstemmed | The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19 |
title_short | The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19 |
title_sort | relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in covid-19 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283482/ https://www.ncbi.nlm.nih.gov/pubmed/33705639 http://dx.doi.org/10.3906/sag-2009-49 |
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