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The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19

BACKGROUND/AIM: It is very important for the efficient use of limited capacity and the success of treatment to predict patients who may need ICU with high mortality rate in the Covid-19 outbreak. In our study, it was aimed to investigate the value of the radiological involvement on initial CT in dem...

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Autores principales: AYDEMİR, Yusuf, GÜNDÜZ, Yasemin, KÖROĞLU, Mehmet, KARABAY, Oğuz, DHEİR, Hamad, ŞENGÜL, Aysun, YAYLACI, Selçuk, KOCAYİĞİT, Havva, ERDEM, Ali Fuat, AYDEMİR, Özlem, GÜÇLÜ, Ertuğrul, YÜRÜMEZ, Yusuf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283482/
https://www.ncbi.nlm.nih.gov/pubmed/33705639
http://dx.doi.org/10.3906/sag-2009-49
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author AYDEMİR, Yusuf
GÜNDÜZ, Yasemin
KÖROĞLU, Mehmet
KARABAY, Oğuz
DHEİR, Hamad
ŞENGÜL, Aysun
YAYLACI, Selçuk
KOCAYİĞİT, Havva
ERDEM, Ali Fuat
AYDEMİR, Özlem
GÜÇLÜ, Ertuğrul
YÜRÜMEZ, Yusuf
author_facet AYDEMİR, Yusuf
GÜNDÜZ, Yasemin
KÖROĞLU, Mehmet
KARABAY, Oğuz
DHEİR, Hamad
ŞENGÜL, Aysun
YAYLACI, Selçuk
KOCAYİĞİT, Havva
ERDEM, Ali Fuat
AYDEMİR, Özlem
GÜÇLÜ, Ertuğrul
YÜRÜMEZ, Yusuf
author_sort AYDEMİR, Yusuf
collection PubMed
description BACKGROUND/AIM: It is very important for the efficient use of limited capacity and the success of treatment to predict patients who may need ICU with high mortality rate in the Covid-19 outbreak. In our study, it was aimed to investigate the value of the radiological involvement on initial CT in demonstrating the ICU transfer and mortality rate of patients. MATERIALS AND METHODS: All PCR-positive patients were included in the study, whose CT, PCR, and laboratory values were obtained simultaneously at the time of first admission. Patients were divided into 4 groups in terms of the extent of radiological lesions. These groups were compared in terms of intensive care transfer needs and Covid-related mortality rates. RESULTS: A total of 477 patients were included in the study. Ninety of them were group 0 (no lung involvement), 162 were group 1 (mild lesion), 89 were group 2 (moderate lesion), and 136 were group 3 (severe lung involvement). A significant relationship was found between the extensiveness of the radiological lesion on CT and admission to intensive care and mortality rate. As the initial radiological involvement amounts increased, the rate of ICU transfer and mortality increased. The mortality rates of the groups were 0%, 3%, 12.3%, and 12.5%, respectively, and the difference was significant (p < 0.001). Similarly, the ICU transfer rates of the groups were 2.2%, 5.6%, 13.5%, and 17.7%, respectively, and the difference was significant (p < 0.001). CONCLUSION: In conclusion, in our study, the strong relationship between the initial radiological extent assessment and the need for intensive care and mortality rates has been demonstrated, and we believe that our results will make a significant contribution to increase the success of the health system in predicting patients who may progress, helping clinicians and managing pandemics.
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spelling pubmed-82834822021-08-02 The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19 AYDEMİR, Yusuf GÜNDÜZ, Yasemin KÖROĞLU, Mehmet KARABAY, Oğuz DHEİR, Hamad ŞENGÜL, Aysun YAYLACI, Selçuk KOCAYİĞİT, Havva ERDEM, Ali Fuat AYDEMİR, Özlem GÜÇLÜ, Ertuğrul YÜRÜMEZ, Yusuf Turk J Med Sci Article BACKGROUND/AIM: It is very important for the efficient use of limited capacity and the success of treatment to predict patients who may need ICU with high mortality rate in the Covid-19 outbreak. In our study, it was aimed to investigate the value of the radiological involvement on initial CT in demonstrating the ICU transfer and mortality rate of patients. MATERIALS AND METHODS: All PCR-positive patients were included in the study, whose CT, PCR, and laboratory values were obtained simultaneously at the time of first admission. Patients were divided into 4 groups in terms of the extent of radiological lesions. These groups were compared in terms of intensive care transfer needs and Covid-related mortality rates. RESULTS: A total of 477 patients were included in the study. Ninety of them were group 0 (no lung involvement), 162 were group 1 (mild lesion), 89 were group 2 (moderate lesion), and 136 were group 3 (severe lung involvement). A significant relationship was found between the extensiveness of the radiological lesion on CT and admission to intensive care and mortality rate. As the initial radiological involvement amounts increased, the rate of ICU transfer and mortality increased. The mortality rates of the groups were 0%, 3%, 12.3%, and 12.5%, respectively, and the difference was significant (p < 0.001). Similarly, the ICU transfer rates of the groups were 2.2%, 5.6%, 13.5%, and 17.7%, respectively, and the difference was significant (p < 0.001). CONCLUSION: In conclusion, in our study, the strong relationship between the initial radiological extent assessment and the need for intensive care and mortality rates has been demonstrated, and we believe that our results will make a significant contribution to increase the success of the health system in predicting patients who may progress, helping clinicians and managing pandemics. The Scientific and Technological Research Council of Turkey 2021-06-28 /pmc/articles/PMC8283482/ /pubmed/33705639 http://dx.doi.org/10.3906/sag-2009-49 Text en Copyright © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Article
AYDEMİR, Yusuf
GÜNDÜZ, Yasemin
KÖROĞLU, Mehmet
KARABAY, Oğuz
DHEİR, Hamad
ŞENGÜL, Aysun
YAYLACI, Selçuk
KOCAYİĞİT, Havva
ERDEM, Ali Fuat
AYDEMİR, Özlem
GÜÇLÜ, Ertuğrul
YÜRÜMEZ, Yusuf
The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19
title The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19
title_full The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19
title_fullStr The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19
title_full_unstemmed The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19
title_short The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19
title_sort relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283482/
https://www.ncbi.nlm.nih.gov/pubmed/33705639
http://dx.doi.org/10.3906/sag-2009-49
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