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Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey

BACKGROUND/AIM: The aim of this descriptive article is to share the experience in Ege University, Turkey with favipiravir in the treatment of severe SARS-CoV-2 pneumonia. MATERIALS AND METHODS: This retrospective descriptive study included patients diagnosed with COVID-19 who presented with or devel...

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Detalles Bibliográficos
Autores principales: ERDEM, Hüseyin Aytaç, KORKMAZ EKREN, Pervin, ÇAĞLAYAN, Derya, IŞIKGÖZ TAŞBAKAN, Meltem, YAMAZHAN, Tansu, TAŞBAKAN, Mehmet Sezai, SAYINER, Abdullah, GÖKENGİN, Deniz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283495/
https://www.ncbi.nlm.nih.gov/pubmed/33237663
http://dx.doi.org/10.3906/sag-2008-33
Descripción
Sumario:BACKGROUND/AIM: The aim of this descriptive article is to share the experience in Ege University, Turkey with favipiravir in the treatment of severe SARS-CoV-2 pneumonia. MATERIALS AND METHODS: This retrospective descriptive study included patients diagnosed with COVID-19 who presented with or developed severe pneumonia. RESULTS: Forty patients who completed a full course (at least 5 days) of favipiravir were included in the study. At baseline, 30 (75%) patients required treatment for respiratory distress. Thirty-three patients (82.5%) were discharged from the hospital with full recovery, 6 patients (15%) died and 1 case (2.5%) was still at the intensive care unit (ICU) when this paper was written. CONCLUSION: This study provides relevant information for the treatment of COVID-19, suggesting that favipiravir was associated with significant clinical and laboratory improvements in the majority of the patients, is a safe drug with no serious side effects and would merit further investigation.