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Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey

BACKGROUND/AIM: The aim of this descriptive article is to share the experience in Ege University, Turkey with favipiravir in the treatment of severe SARS-CoV-2 pneumonia. MATERIALS AND METHODS: This retrospective descriptive study included patients diagnosed with COVID-19 who presented with or devel...

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Autores principales: ERDEM, Hüseyin Aytaç, KORKMAZ EKREN, Pervin, ÇAĞLAYAN, Derya, IŞIKGÖZ TAŞBAKAN, Meltem, YAMAZHAN, Tansu, TAŞBAKAN, Mehmet Sezai, SAYINER, Abdullah, GÖKENGİN, Deniz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283495/
https://www.ncbi.nlm.nih.gov/pubmed/33237663
http://dx.doi.org/10.3906/sag-2008-33
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author ERDEM, Hüseyin Aytaç
KORKMAZ EKREN, Pervin
ÇAĞLAYAN, Derya
IŞIKGÖZ TAŞBAKAN, Meltem
YAMAZHAN, Tansu
TAŞBAKAN, Mehmet Sezai
SAYINER, Abdullah
GÖKENGİN, Deniz
author_facet ERDEM, Hüseyin Aytaç
KORKMAZ EKREN, Pervin
ÇAĞLAYAN, Derya
IŞIKGÖZ TAŞBAKAN, Meltem
YAMAZHAN, Tansu
TAŞBAKAN, Mehmet Sezai
SAYINER, Abdullah
GÖKENGİN, Deniz
author_sort ERDEM, Hüseyin Aytaç
collection PubMed
description BACKGROUND/AIM: The aim of this descriptive article is to share the experience in Ege University, Turkey with favipiravir in the treatment of severe SARS-CoV-2 pneumonia. MATERIALS AND METHODS: This retrospective descriptive study included patients diagnosed with COVID-19 who presented with or developed severe pneumonia. RESULTS: Forty patients who completed a full course (at least 5 days) of favipiravir were included in the study. At baseline, 30 (75%) patients required treatment for respiratory distress. Thirty-three patients (82.5%) were discharged from the hospital with full recovery, 6 patients (15%) died and 1 case (2.5%) was still at the intensive care unit (ICU) when this paper was written. CONCLUSION: This study provides relevant information for the treatment of COVID-19, suggesting that favipiravir was associated with significant clinical and laboratory improvements in the majority of the patients, is a safe drug with no serious side effects and would merit further investigation.
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spelling pubmed-82834952021-08-02 Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey ERDEM, Hüseyin Aytaç KORKMAZ EKREN, Pervin ÇAĞLAYAN, Derya IŞIKGÖZ TAŞBAKAN, Meltem YAMAZHAN, Tansu TAŞBAKAN, Mehmet Sezai SAYINER, Abdullah GÖKENGİN, Deniz Turk J Med Sci Article BACKGROUND/AIM: The aim of this descriptive article is to share the experience in Ege University, Turkey with favipiravir in the treatment of severe SARS-CoV-2 pneumonia. MATERIALS AND METHODS: This retrospective descriptive study included patients diagnosed with COVID-19 who presented with or developed severe pneumonia. RESULTS: Forty patients who completed a full course (at least 5 days) of favipiravir were included in the study. At baseline, 30 (75%) patients required treatment for respiratory distress. Thirty-three patients (82.5%) were discharged from the hospital with full recovery, 6 patients (15%) died and 1 case (2.5%) was still at the intensive care unit (ICU) when this paper was written. CONCLUSION: This study provides relevant information for the treatment of COVID-19, suggesting that favipiravir was associated with significant clinical and laboratory improvements in the majority of the patients, is a safe drug with no serious side effects and would merit further investigation. The Scientific and Technological Research Council of Turkey 2021-06-28 /pmc/articles/PMC8283495/ /pubmed/33237663 http://dx.doi.org/10.3906/sag-2008-33 Text en Copyright © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Article
ERDEM, Hüseyin Aytaç
KORKMAZ EKREN, Pervin
ÇAĞLAYAN, Derya
IŞIKGÖZ TAŞBAKAN, Meltem
YAMAZHAN, Tansu
TAŞBAKAN, Mehmet Sezai
SAYINER, Abdullah
GÖKENGİN, Deniz
Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey
title Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey
title_full Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey
title_fullStr Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey
title_full_unstemmed Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey
title_short Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey
title_sort treatment of sars-cov-2 pneumonia with favipiravir: early results from the ege university cohort, turkey
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283495/
https://www.ncbi.nlm.nih.gov/pubmed/33237663
http://dx.doi.org/10.3906/sag-2008-33
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