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Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey
BACKGROUND/AIM: The aim of this descriptive article is to share the experience in Ege University, Turkey with favipiravir in the treatment of severe SARS-CoV-2 pneumonia. MATERIALS AND METHODS: This retrospective descriptive study included patients diagnosed with COVID-19 who presented with or devel...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Scientific and Technological Research Council of Turkey
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283495/ https://www.ncbi.nlm.nih.gov/pubmed/33237663 http://dx.doi.org/10.3906/sag-2008-33 |
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author | ERDEM, Hüseyin Aytaç KORKMAZ EKREN, Pervin ÇAĞLAYAN, Derya IŞIKGÖZ TAŞBAKAN, Meltem YAMAZHAN, Tansu TAŞBAKAN, Mehmet Sezai SAYINER, Abdullah GÖKENGİN, Deniz |
author_facet | ERDEM, Hüseyin Aytaç KORKMAZ EKREN, Pervin ÇAĞLAYAN, Derya IŞIKGÖZ TAŞBAKAN, Meltem YAMAZHAN, Tansu TAŞBAKAN, Mehmet Sezai SAYINER, Abdullah GÖKENGİN, Deniz |
author_sort | ERDEM, Hüseyin Aytaç |
collection | PubMed |
description | BACKGROUND/AIM: The aim of this descriptive article is to share the experience in Ege University, Turkey with favipiravir in the treatment of severe SARS-CoV-2 pneumonia. MATERIALS AND METHODS: This retrospective descriptive study included patients diagnosed with COVID-19 who presented with or developed severe pneumonia. RESULTS: Forty patients who completed a full course (at least 5 days) of favipiravir were included in the study. At baseline, 30 (75%) patients required treatment for respiratory distress. Thirty-three patients (82.5%) were discharged from the hospital with full recovery, 6 patients (15%) died and 1 case (2.5%) was still at the intensive care unit (ICU) when this paper was written. CONCLUSION: This study provides relevant information for the treatment of COVID-19, suggesting that favipiravir was associated with significant clinical and laboratory improvements in the majority of the patients, is a safe drug with no serious side effects and would merit further investigation. |
format | Online Article Text |
id | pubmed-8283495 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Scientific and Technological Research Council of Turkey |
record_format | MEDLINE/PubMed |
spelling | pubmed-82834952021-08-02 Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey ERDEM, Hüseyin Aytaç KORKMAZ EKREN, Pervin ÇAĞLAYAN, Derya IŞIKGÖZ TAŞBAKAN, Meltem YAMAZHAN, Tansu TAŞBAKAN, Mehmet Sezai SAYINER, Abdullah GÖKENGİN, Deniz Turk J Med Sci Article BACKGROUND/AIM: The aim of this descriptive article is to share the experience in Ege University, Turkey with favipiravir in the treatment of severe SARS-CoV-2 pneumonia. MATERIALS AND METHODS: This retrospective descriptive study included patients diagnosed with COVID-19 who presented with or developed severe pneumonia. RESULTS: Forty patients who completed a full course (at least 5 days) of favipiravir were included in the study. At baseline, 30 (75%) patients required treatment for respiratory distress. Thirty-three patients (82.5%) were discharged from the hospital with full recovery, 6 patients (15%) died and 1 case (2.5%) was still at the intensive care unit (ICU) when this paper was written. CONCLUSION: This study provides relevant information for the treatment of COVID-19, suggesting that favipiravir was associated with significant clinical and laboratory improvements in the majority of the patients, is a safe drug with no serious side effects and would merit further investigation. The Scientific and Technological Research Council of Turkey 2021-06-28 /pmc/articles/PMC8283495/ /pubmed/33237663 http://dx.doi.org/10.3906/sag-2008-33 Text en Copyright © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Article ERDEM, Hüseyin Aytaç KORKMAZ EKREN, Pervin ÇAĞLAYAN, Derya IŞIKGÖZ TAŞBAKAN, Meltem YAMAZHAN, Tansu TAŞBAKAN, Mehmet Sezai SAYINER, Abdullah GÖKENGİN, Deniz Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey |
title | Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey |
title_full | Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey |
title_fullStr | Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey |
title_full_unstemmed | Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey |
title_short | Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey |
title_sort | treatment of sars-cov-2 pneumonia with favipiravir: early results from the ege university cohort, turkey |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283495/ https://www.ncbi.nlm.nih.gov/pubmed/33237663 http://dx.doi.org/10.3906/sag-2008-33 |
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