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Molecular Dynamics Simulations Reveal Interactions of an IgG1 Antibody With Selected Fc Receptors
In a survey of novel interactions between an IgG1 antibody and different Fcγ receptors (FcγR), molecular dynamics simulations were performed of interactions of monoclonal antibody involved complexes with FcγRs. Free energy simulations were also performed of isolated wild-type and substituted Fc regi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283507/ https://www.ncbi.nlm.nih.gov/pubmed/34277572 http://dx.doi.org/10.3389/fchem.2021.705931 |