Epstein-Barr Virus (EBV) acute acalculous cholecystitis in an immunocompromised adult patient: a case report and a literature review of a neglected clinical presentation

Primary Epstein-Barr virus (EBV) infection may present with self-limiting abdominal involvement, characterized by hepatitis with mild elevation of aminotransferases, splenomegaly, and rarely with acute acalculous cholecystitis (AAC). Usually, treatment of EBV related AAC is symptomatic, without the...

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Autores principales: BONINSEGNA, SARA, STORATO, SILVIA, RICCARDI, NICCOLÒ, SOPRANA, MARCO, OLIBONI, EUGENIO, TAMAROZZI, FRANCESCA, BOCUS, PAOLO, MARTINI, MARIANO, FLOREANI, ANNAROSA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore Srl 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283645/
https://www.ncbi.nlm.nih.gov/pubmed/34322642
http://dx.doi.org/10.15167/2421-4248/jpmh2021.62.1.1859
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author BONINSEGNA, SARA
STORATO, SILVIA
RICCARDI, NICCOLÒ
SOPRANA, MARCO
OLIBONI, EUGENIO
TAMAROZZI, FRANCESCA
BOCUS, PAOLO
MARTINI, MARIANO
FLOREANI, ANNAROSA
author_facet BONINSEGNA, SARA
STORATO, SILVIA
RICCARDI, NICCOLÒ
SOPRANA, MARCO
OLIBONI, EUGENIO
TAMAROZZI, FRANCESCA
BOCUS, PAOLO
MARTINI, MARIANO
FLOREANI, ANNAROSA
author_sort BONINSEGNA, SARA
collection PubMed
description Primary Epstein-Barr virus (EBV) infection may present with self-limiting abdominal involvement, characterized by hepatitis with mild elevation of aminotransferases, splenomegaly, and rarely with acute acalculous cholecystitis (AAC). Usually, treatment of EBV related AAC is symptomatic, without the need for surgery. Here, we describe a severe case of AAC occurring as the first manifestation of infectious mononucleosis in a young adult woman, receiving treatment with interleukin 6 receptor (IL-6r) inhibitor for rheumatoid arthritis (RA); moreover, we have performed a review of the literature on EBV-related AAC.
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spelling pubmed-82836452021-07-27 Epstein-Barr Virus (EBV) acute acalculous cholecystitis in an immunocompromised adult patient: a case report and a literature review of a neglected clinical presentation BONINSEGNA, SARA STORATO, SILVIA RICCARDI, NICCOLÒ SOPRANA, MARCO OLIBONI, EUGENIO TAMAROZZI, FRANCESCA BOCUS, PAOLO MARTINI, MARIANO FLOREANI, ANNAROSA J Prev Med Hyg Review Primary Epstein-Barr virus (EBV) infection may present with self-limiting abdominal involvement, characterized by hepatitis with mild elevation of aminotransferases, splenomegaly, and rarely with acute acalculous cholecystitis (AAC). Usually, treatment of EBV related AAC is symptomatic, without the need for surgery. Here, we describe a severe case of AAC occurring as the first manifestation of infectious mononucleosis in a young adult woman, receiving treatment with interleukin 6 receptor (IL-6r) inhibitor for rheumatoid arthritis (RA); moreover, we have performed a review of the literature on EBV-related AAC. Pacini Editore Srl 2021-04-29 /pmc/articles/PMC8283645/ /pubmed/34322642 http://dx.doi.org/10.15167/2421-4248/jpmh2021.62.1.1859 Text en ©2021 Pacini Editore SRL, Pisa, Italy https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed in accordance with the CC-BY-NC-ND (Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International) license. The article can be used by giving appropriate credit and mentioning the license, but only for non-commercial purposes and only in the original version. For further information: https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en
spellingShingle Review
BONINSEGNA, SARA
STORATO, SILVIA
RICCARDI, NICCOLÒ
SOPRANA, MARCO
OLIBONI, EUGENIO
TAMAROZZI, FRANCESCA
BOCUS, PAOLO
MARTINI, MARIANO
FLOREANI, ANNAROSA
Epstein-Barr Virus (EBV) acute acalculous cholecystitis in an immunocompromised adult patient: a case report and a literature review of a neglected clinical presentation
title Epstein-Barr Virus (EBV) acute acalculous cholecystitis in an immunocompromised adult patient: a case report and a literature review of a neglected clinical presentation
title_full Epstein-Barr Virus (EBV) acute acalculous cholecystitis in an immunocompromised adult patient: a case report and a literature review of a neglected clinical presentation
title_fullStr Epstein-Barr Virus (EBV) acute acalculous cholecystitis in an immunocompromised adult patient: a case report and a literature review of a neglected clinical presentation
title_full_unstemmed Epstein-Barr Virus (EBV) acute acalculous cholecystitis in an immunocompromised adult patient: a case report and a literature review of a neglected clinical presentation
title_short Epstein-Barr Virus (EBV) acute acalculous cholecystitis in an immunocompromised adult patient: a case report and a literature review of a neglected clinical presentation
title_sort epstein-barr virus (ebv) acute acalculous cholecystitis in an immunocompromised adult patient: a case report and a literature review of a neglected clinical presentation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283645/
https://www.ncbi.nlm.nih.gov/pubmed/34322642
http://dx.doi.org/10.15167/2421-4248/jpmh2021.62.1.1859
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