Cargando…

DPYD, down-regulated by the potentially chemopreventive agent luteolin, interacts with STAT3 in pancreatic cancer

The 5-year survival rate of pancreatic ductal carcinoma (PDAC) patients is <10% despite progress in clinical medicine. Strategies to prevent the development of PDAC are urgently required. The flavonoids Luteolin (Lut) and hesperetin (Hes) may be cancer-chemopreventive, but effects on pancreatic c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kato, Hiroyuki, Naiki-Ito, Aya, Suzuki, Shugo, Inaguma, Shingo, Komura, Masayuki, Nakao, Kenju, Naiki, Taku, Kachi, Kenta, Kato, Akihisa, Matsuo, Yoichi, Takahashi, Satoru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Inflammation, Microenvironment and Prevention
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283735/ https://www.ncbi.nlm.nih.gov/pubmed/33640964 http://dx.doi.org/10.1093/carcin/bgab017

Ejemplares similares

Recruitment of miR-8080 by luteolin inhibits androgen receptor splice variant 7 expression in castration-resistant prostate cancer
por: Naiki-Ito, Aya, et al.
Publicado: (2020)

Anti-Allergic Drug Suppressed Pancreatic Carcinogenesis via Down-Regulation of Cellular Proliferation
por: Kachi, Kenta, et al.
Publicado: (2021)

Butyrate delivered by butyrylated starch increases distal colonic epithelial apoptosis in carcinogen-treated rats
por: Clarke, Julie M., et al.
Publicado: (2012)

Consumption of high ω-3 fatty acid diet suppressed prostate tumorigenesis in C3(1) Tag mice
por: Akinsete, Juliana A., et al.
Publicado: (2012)

Eicosapentaenoic acid attenuates obesity-related hepatocellular carcinogenesis
por: Inoue-Yamauchi, Akane, et al.
Publicado: (2018)

Urolithin A gains in antiproliferative capacity by reducing the glycolytic potential via the p53/TIGAR axis in colon cancer cells
por: Norden, Elisabeth, et al.
Publicado: (2019)

3,3-Diindolylmethane (DIM): a nutritional intervention and its impact on breast density in healthy BRCA carriers. A prospective clinical trial
por: Yerushalmi, Rinat, et al.
Publicado: (2020)

Dietary interventions to prevent high-fructose diet–associated worsening of colitis and colitis-associated tumorigenesis in mice
por: Nishiguchi, Ryohei, et al.
Publicado: (2021)

Appearance of peanut agglutinin in the blood circulation after peanut ingestion promotes endothelial secretion of metastasis-promoting cytokines
por: Wang, Weikun, et al.
Publicado: (2021)

Fenretinide combines perturbation of signaling kinases, cell–extracellular matrix interactions and matrix metalloproteinase activation to inhibit invasion in oral squamous cell carcinoma cells
por: Wang, Daren, et al.
Publicado: (2022)

Dual roles of cellular communication network factor 6 (CCN6) in the invasion and metastasis of oral cancer cells to bone via binding to BMP2 and RANKL
por: Hochi, Hiroaki, et al.
Publicado: (2023)

Suppressive Effect and Molecular Mechanism of Houttuynia cordata Thunb. Extract against Prostate Carcinogenesis and Castration-Resistant Prostate Cancer
por: Subhawa, Subhawat, et al.
Publicado: (2021)

A novel model of non-alcoholic steatohepatitis with fibrosis and carcinogenesis in connexin 32 dominant-negative transgenic rats
por: Naiki-Ito, Aya, et al.
Publicado: (2020)

Luteolin suppresses bladder cancer growth via regulation of mechanistic target of rapamycin pathway
por: Iida, Keitaro, et al.
Publicado: (2020)

Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis
por: Kato, Hiroyuki, et al.
Publicado: (2015)

Hexane Insoluble Fraction from Purple Rice Extract Retards Carcinogenesis and Castration-Resistant Cancer Growth of Prostate through Suppression of Androgen Receptor Mediated Cell Proliferation and Metabolism
por: Yeewa, Ranchana, et al.
Publicado: (2020)

Lactoferrin Prevents Hepatic Injury and Fibrosis via the Inhibition of NF-κB Signaling in a Rat Non-Alcoholic Steatohepatitis Model
por: Aoyama, Yoshinaga, et al.
Publicado: (2021)

Chemopreventive effects of angiotensin II receptor type 2 agonist on prostate carcinogenesis by the down-regulation of the androgen receptor
por: Ito, Yusuke, et al.
Publicado: (2018)

Establishment of a syngeneic orthotopic model of prostate cancer in immunocompetent rats
por: Suzuki, Shugo, et al.
Publicado: (2014)

Concomitant Pancreatic Ductal Adenocarcinoma and Type 1 Autoimmune Pancreatitis: A Potential Issue in the Diagnosis of Carcinoma by Endoscopic Ultrasound-guided Fine-needle Biopsy
por: Kachi, Kenta, et al.
Publicado: (2022)

GPX2 promotes development of bladder cancer with squamous cell differentiation through the control of apoptosis
por: Naiki, Taku, et al.
Publicado: (2018)

Chemopreventive effect of resveratrol and apocynin on pancreatic carcinogenesis via modulation of nuclear phosphorylated GSK3β and ERK1/2
por: Kato, Akihisa, et al.
Publicado: (2015)

NCL1, A Highly Selective Lysine-Specific Demethylase 1 Inhibitor, Suppresses Castration-Resistant Prostate Cancer Growth via Regulation of Apoptosis and Autophagy
por: Etani, Toshiki, et al.
Publicado: (2019)

Preventive Effects of Fermented Brown Rice and Rice Bran on Spontaneous Lymphomagenesis in AKR/NSlc Female Mice
por: Kuno, Toshiya, et al.
Publicado: (2018)

Pioglitazone, a Peroxisome Proliferator-Activated Receptor γ Agonist, Suppresses Rat Prostate Carcinogenesis
por: Suzuki, Shugo, et al.
Publicado: (2016)

Preventive Effects of Fermented Brown Rice and Rice Bran against Prostate Carcinogenesis in TRAP Rats
por: Kuno, Toshiya, et al.
Publicado: (2016)

Role of γ-H2AX as a biomarker for detection of bladder carcinogens in F344 rats
por: Suzuki, Shugo, et al.
Publicado: (2020)

Cyclohexanone curcumin analogs inhibit the progression of castration‐resistant prostate cancer in vitro and in vivo
por: Mapoung, Sariya, et al.
Publicado: (2018)

Novel case of androgen receptor‐positive cancer of unknown primary without serum prostate‐specific antigen elevation that became progression free in the long term after primary combined androgen blockade
por: Matsuyama, Nayuka, et al.
Publicado: (2020)

Rare case of carcinoma in situ originated in right retrocaval ureter successfully managed with laparoscopic procedure
por: Noda, Yusuke, et al.
Publicado: (2020)

Selective lysine‐specific demethylase 1 inhibitor, NCL1, could cause testicular toxicity via the regulation of apoptosis
por: Nozaki, Satoshi, et al.
Publicado: (2020)

Establishment of an Invasive Prostate Cancer Model in Transgenic Rats by Intermittent Testosterone Administration
por: Sato, Shinya, et al.
Publicado: (2014)

Dimethylarsinic acid may promote prostate carcinogenesis in rats
por: Suzuki, Shugo, et al.
Publicado: (2018)

Dehydrozingerone, a Curcumin Analog, as a Potential Anti-Prostate Cancer Inhibitor In Vitro and In Vivo
por: Mapoung, Sariya, et al.
Publicado: (2020)

Diurnal Expression of PD-1 on Tumor-Associated Macrophages Underlies the Dosing Time-Dependent Antitumor Effects of the PD-1/PD-L1 Inhibitor BMS-1 in B16/BL6 Melanoma-Bearing Mice
por: Tsuruta, Akito, et al.
Publicado: (2022)

Usefulness of advanced monoenergetic reconstruction technique in dual-energy computed tomography for detecting bladder cancer
por: Nakagawa, Motoo, et al.
Publicado: (2021)

Metachronous Pancreatic Ductal Adenocarcinoma with Adjacent Serous Cystadenoma that Was Preoperatively Diagnosed by EUS-FNA: A Case Report and Review of the Literature
por: Yoshida, Michihiro, et al.
Publicado: (2019)

Monthly malaria chemoprevention shows potential in an area of very high, perennial malaria transmission
por: Cairns, Matthew, et al.
Publicado: (2015)

Short-term detection of gastric genotoxicity using the DNA double-strand break marker γ-H2AX
por: Okabe, Asako, et al.
Publicado: (2019)

A Case of Renal Primitive Neuroectodermal Tumor Confirmed by Fluorescence in situ Hybridization
por: Etani, Toshiki, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_hnvp13u3qhkj75voui42vs6t6c