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U5 snRNA Interactions With Exons Ensure Splicing Precision
Imperfect conservation of human pre-mRNA splice sites is necessary to produce alternative isoforms. This flexibility is combined with the precision of the message reading frame. Apart from intron-termini GU_AG and the branchpoint A, the most conserved are the exon-end guanine and +5G of the intron s...
Autores principales: | Artemyeva-Isman, Olga V., Porter, Andrew C. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283771/ https://www.ncbi.nlm.nih.gov/pubmed/34276781 http://dx.doi.org/10.3389/fgene.2021.676971 |
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