Cargando…

Evidence That Tumor Microenvironment Initiates Epithelial-To-Mesenchymal Transition and Calebin A can Suppress it in Colorectal Cancer Cells

Background: Tumor microenvironment (TME) has a pivotal impact on tumor progression, and epithelial-mesenchymal transition (EMT) is an extremely crucial initial event in the metastatic process in colorectal cancer (CRC) that is not yet fully understood. Calebin A (an ingredient in Curcuma longa) has...

Descripción completa

Detalles Bibliográficos
Autores principales:	Buhrmann, Constanze, Brockmueller, Aranka, Harsha, Choudhary, Kunnumakkara, Ajaikumar B., Kubatka, Peter, Aggarwal, Bharat B., Shakibaei, Mehdi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283792/ https://www.ncbi.nlm.nih.gov/pubmed/34276382 http://dx.doi.org/10.3389/fphar.2021.699842

Ejemplares similares

Multitargeting Effects of Calebin A on Malignancy of CRC Cells in Multicellular Tumor Microenvironment
por: Buhrmann, Constanze, et al.
Publicado: (2021)

Multifunctionality of Calebin A in inflammation, chronic diseases and cancer
por: Brockmueller, Aranka, et al.
Publicado: (2022)

Calebin A targets the HIF-1α/NF-κB pathway to suppress colorectal cancer cell migration
por: Brockmueller, Aranka, et al.
Publicado: (2023)

Calebin A, a Compound of Turmeric, Down-Regulates Inflammation in Tenocytes by NF-κB/Scleraxis Signaling
por: Mueller, Anna-Lena, et al.
Publicado: (2022)

Targeting NF-κB Signaling by Calebin A, a Compound of Turmeric, in Multicellular Tumor Microenvironment: Potential Role of Apoptosis Induction in CRC Cells
por: Buhrmann, Constanze, et al.
Publicado: (2020)

Evidence That Calebin A, a Component of Curcuma Longa Suppresses NF-κB Mediated Proliferation, Invasion and Metastasis of Human Colorectal Cancer Induced by TNF-β (Lymphotoxin)
por: Buhrmann, Constanze, et al.
Publicado: (2019)

Calebin A Potentiates the Effect of 5-FU and TNF-β (Lymphotoxin α) against Human Colorectal Cancer Cells: Potential Role of NF-κB †
por: Buhrmann, Constanze, et al.
Publicado: (2020)

Induction of the Epithelial-to-Mesenchymal Transition of Human Colorectal Cancer by Human TNF-β (Lymphotoxin) and its Reversal by Resveratrol
por: Buhrmann, Constanze, et al.
Publicado: (2019)

Resveratrol Modulates Chemosensitisation to 5-FU via β1-Integrin/HIF-1α Axis in CRC Tumor Microenvironment
por: Brockmueller, Aranka, et al.
Publicado: (2023)

Resveratrol Suppresses Cross-Talk between Colorectal Cancer Cells and Stromal Cells in Multicellular Tumor Microenvironment: A Bridge between In Vitro and In Vivo Tumor Microenvironment Study
por: Buhrmann, Constanze, et al.
Publicado: (2020)

Resveratrol induces apoptosis by modulating the reciprocal crosstalk between p53 and Sirt-1 in the CRC tumor microenvironment
por: Brockmueller, Aranka, et al.
Publicado: (2023)

Modulation of Inflammation by Plant-Derived Nutraceuticals in Tendinitis
por: Mueller, Anna-Lena, et al.
Publicado: (2022)

β1-Integrin plays a major role in resveratrol-mediated anti-invasion effects in the CRC microenvironment
por: Brockmueller, Aranka, et al.
Publicado: (2022)

Curcumin Attenuates Environment-Derived Osteoarthritis by Sox9/NF-kB Signaling Axis
por: Buhrmann, Constanze, et al.
Publicado: (2021)

Bacteria-Mediated Modulatory Strategies for Colorectal Cancer Treatment
por: Mueller, Anna-Lena, et al.
Publicado: (2022)

Googling the Guggul (Commiphora and Boswellia) for Prevention of Chronic Diseases
por: Kunnumakkara, Ajaikumar B., et al.
Publicado: (2018)

Evidence that TNF-β (lymphotoxin α) can activate the inflammatory environment in human chondrocytes
por: Buhrmann, Constanze, et al.
Publicado: (2013)

Resveratrol downregulates inflammatory pathway activated by lymphotoxin α (TNF-β) in articular chondrocytes: Comparison with TNF-α
por: Buhrmann, Constanze, et al.
Publicado: (2017)

Curcumin mediated suppression of nuclear factor-κB promotes chondrogenic differentiation of mesenchymal stem cells in a high-density co-culture microenvironment
por: Buhrmann, Constanze, et al.
Publicado: (2010)

Evidence That β1-Integrin Is Required for the Anti-Viability and Anti-Proliferative Effect of Resveratrol in CRC Cells
por: Brockmueller, Aranka, et al.
Publicado: (2022)

Resveratrol Chemosensitizes TNF-β-Induced Survival of 5-FU-Treated Colorectal Cancer Cells
por: Buhrmann, Constanze, et al.
Publicado: (2018)

Resveratrol’s Anti-Cancer Effects through the Modulation of Tumor Glucose Metabolism
por: Brockmueller, Aranka, et al.
Publicado: (2021)

Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancer
por: Shakibaei, Mehdi, et al.
Publicado: (2015)

Curcumin Suppresses Crosstalk between Colon Cancer Stem Cells and Stromal Fibroblasts in the Tumor Microenvironment: Potential Role of EMT
por: Buhrmann, Constanze, et al.
Publicado: (2014)

Resveratrol-mediated SIRT-1 Interactions with p300 Modulate Receptor Activator of NF-κB Ligand (RANKL) Activation of NF-κB Signaling and Inhibit Osteoclastogenesis in Bone-derived Cells
por: Shakibaei, Mehdi, et al.
Publicado: (2011)

Inflammation, a Double-Edge Sword for Cancer and Other Age-Related Diseases
por: Gupta, Subash Chandra, et al.
Publicado: (2018)

Curcumin, inflammation, and neurological disorders: How are they linked?
por: Garodia, Prachi, et al.
Publicado: (2023)

Chronic diseases, inflammation, and spices: how are they linked?
por: Kunnumakkara, Ajaikumar B., et al.
Publicado: (2018)

Curcumin’s Beneficial Effects on Neuroblastoma: Mechanisms, Challenges, and Potential Solutions
por: Zhai, Kevin, et al.
Publicado: (2020)

Potential of guggulsterone, a farnesoid X receptor antagonist, in the prevention and treatment of cancer
por: Girisa, Sosmitha, et al.
Publicado: (2020)

Resveratrol Regulates Colorectal Cancer Cell Invasion by Modulation of Focal Adhesion Molecules
por: Buhrmann, Constanze, et al.
Publicado: (2017)

Resveratrol Mediated Modulation of Sirt-1/Runx2 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells: Potential Role of Runx2 Deacetylation
por: Shakibaei, Mehdi, et al.
Publicado: (2012)

Bacterial lipopolysaccharides form procollagen-endotoxin complexes that trigger cartilage inflammation and degeneration: implications for the development of rheumatoid arthritis
por: Lorenz, Wolfgang, et al.
Publicado: (2013)

Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells
por: Buhrmann, Constanze, et al.
Publicado: (2016)

Carotenoids in Cancer Metastasis—Status Quo and Outlook
por: Koklesova, Lenka, et al.
Publicado: (2020)

Natural Plants Compounds as Modulators of Epithelial-to-Mesenchymal Transition
por: Avila-Carrasco, Lorena, et al.
Publicado: (2019)

Tackle Epithelial-Mesenchymal Transition With Epigenetic Drugs in Cancer
por: Dong, Bo, et al.
Publicado: (2020)

Epithelial-to-Mesenchymal Transition in Fibrosis: Concepts and Targeting Strategies
por: Lovisa, Sara
Publicado: (2021)

microRNA Crosstalk Influences Epithelial-to-Mesenchymal, Endothelial-to-Mesenchymal, and Macrophage-to-Mesenchymal Transitions in the Kidney
por: Srivastava, Swayam Prakash, et al.
Publicado: (2019)

Erratum: microRNA Crosstalk Influences Epithelial-to-Mesenchymal, Endothelial-to-Mesenchymal, and Macrophage-to-Mesenchymal Transitions in the Kidney
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_857c7fouruav5rbjpbtd8bgult