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Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease
In this work, we present the first steps toward the creation of a new neurorobotics model of Parkinson's Disease (PD) that embeds, for the first time in a real robot, a well-established computational model of PD. PD mostly affects the modulation of movement in humans. The number of people suffe...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283825/ https://www.ncbi.nlm.nih.gov/pubmed/34276331 http://dx.doi.org/10.3389/fnbot.2021.640449 |
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author | Pimentel, Jhielson M. Moioli, Renan C. de Araujo, Mariana F. P. Ranieri, Caetano M. Romero, Roseli A. F. Broz, Frank Vargas, Patricia A. |
author_facet | Pimentel, Jhielson M. Moioli, Renan C. de Araujo, Mariana F. P. Ranieri, Caetano M. Romero, Roseli A. F. Broz, Frank Vargas, Patricia A. |
author_sort | Pimentel, Jhielson M. |
collection | PubMed |
description | In this work, we present the first steps toward the creation of a new neurorobotics model of Parkinson's Disease (PD) that embeds, for the first time in a real robot, a well-established computational model of PD. PD mostly affects the modulation of movement in humans. The number of people suffering from this neurodegenerative disease is set to double in the next 15 years and there is still no cure. With the new model we were capable to further explore the dynamics of the disease using a humanoid robot. Results show that the embedded model under both conditions, healthy and parkinsonian, was capable of performing a simple behavioural task with different levels of motor disturbance. We believe that this neurorobotics model is a stepping stone to the development of more sophisticated models that could eventually test and inform new PD therapies and help to reduce and replace animals in research. |
format | Online Article Text |
id | pubmed-8283825 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82838252021-07-17 Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease Pimentel, Jhielson M. Moioli, Renan C. de Araujo, Mariana F. P. Ranieri, Caetano M. Romero, Roseli A. F. Broz, Frank Vargas, Patricia A. Front Neurorobot Neuroscience In this work, we present the first steps toward the creation of a new neurorobotics model of Parkinson's Disease (PD) that embeds, for the first time in a real robot, a well-established computational model of PD. PD mostly affects the modulation of movement in humans. The number of people suffering from this neurodegenerative disease is set to double in the next 15 years and there is still no cure. With the new model we were capable to further explore the dynamics of the disease using a humanoid robot. Results show that the embedded model under both conditions, healthy and parkinsonian, was capable of performing a simple behavioural task with different levels of motor disturbance. We believe that this neurorobotics model is a stepping stone to the development of more sophisticated models that could eventually test and inform new PD therapies and help to reduce and replace animals in research. Frontiers Media S.A. 2021-07-01 /pmc/articles/PMC8283825/ /pubmed/34276331 http://dx.doi.org/10.3389/fnbot.2021.640449 Text en Copyright © 2021 Pimentel, Moioli, de Araujo, Ranieri, Romero, Broz and Vargas. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Pimentel, Jhielson M. Moioli, Renan C. de Araujo, Mariana F. P. Ranieri, Caetano M. Romero, Roseli A. F. Broz, Frank Vargas, Patricia A. Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease |
title | Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease |
title_full | Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease |
title_fullStr | Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease |
title_full_unstemmed | Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease |
title_short | Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease |
title_sort | neuro4pd: an initial neurorobotics model of parkinson's disease |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283825/ https://www.ncbi.nlm.nih.gov/pubmed/34276331 http://dx.doi.org/10.3389/fnbot.2021.640449 |
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