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Updating the NLRC4 Inflammasome: from Bacterial Infections to Autoimmunity and Cancer
Inflammasomes comprise a family of cytosolic multi-protein complexes that modulate the activation of cysteine-aspartate-specific protease 1 (caspase-1) and promote the maturation and secretion of interleukin (IL)-1β and IL-18, leading to an inflammatory response. Different types of inflammasomes are...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283967/ https://www.ncbi.nlm.nih.gov/pubmed/34276697 http://dx.doi.org/10.3389/fimmu.2021.702527 |