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Updating the NLRC4 Inflammasome: from Bacterial Infections to Autoimmunity and Cancer

Inflammasomes comprise a family of cytosolic multi-protein complexes that modulate the activation of cysteine-aspartate-specific protease 1 (caspase-1) and promote the maturation and secretion of interleukin (IL)-1β and IL-18, leading to an inflammatory response. Different types of inflammasomes are...

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Detalles Bibliográficos
Autores principales:	Wen, Jiexia, Xuan, Bin, Liu, Yang, Wang, Liwei, He, Li, Meng, Xiangcai, Zhou, Tao, Wang, Yimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283967/ https://www.ncbi.nlm.nih.gov/pubmed/34276697 http://dx.doi.org/10.3389/fimmu.2021.702527

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