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The requirement of hemodialysis in patients with acute gastroenteritis–induced acute kidney injury

Acute gastroenteritis is an important cause of preventable acute kidney injury (AKI). Inadequate or delayed restoration of diarrheal losses results in a very high incidence of AKI. Diarrheal illness is a major reason for hospitalization, but data on consequent acute kidney injury are sparse. The obj...

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Autores principales: Bhakthavatchalam, Supriyaa, Srinivasan, Devasena, Prithviraj, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284204/
https://www.ncbi.nlm.nih.gov/pubmed/34322450
http://dx.doi.org/10.4103/jfmpc.jfmpc_1979_20
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author Bhakthavatchalam, Supriyaa
Srinivasan, Devasena
Prithviraj, R
author_facet Bhakthavatchalam, Supriyaa
Srinivasan, Devasena
Prithviraj, R
author_sort Bhakthavatchalam, Supriyaa
collection PubMed
description Acute gastroenteritis is an important cause of preventable acute kidney injury (AKI). Inadequate or delayed restoration of diarrheal losses results in a very high incidence of AKI. Diarrheal illness is a major reason for hospitalization, but data on consequent acute kidney injury are sparse. The objective of the study is to determine the incidence of AKI in infectious and noninfectious diarrheal illness requiring hospitalization and to identify correlates and outcomes of diarrhea-associated AKI. None of the patients had any organism isolated in stool, probably due to prompt initiation of antibiotics/inadequate culture growth. Three out of our 6 cases did not require hemodialysis (HD) and AKI resolved on conservative management alone (fluids, electrolyte management, and antibiotics). Three out of 6 cases had nonresolving AKI and were dependent on renal replacement therapy (RRT) even at 1 month after discharge as they remained oliguric. One recent paper has reported the recovery of renal function after a period of dialysis. Frequent electrolyte abnormalities, risk of (catheter-related/bloodstream) infections, and severity of the primary disease are the chief reasons for the persistently high morbidity. Although, there was no mortality in our study.
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spelling pubmed-82842042021-07-27 The requirement of hemodialysis in patients with acute gastroenteritis–induced acute kidney injury Bhakthavatchalam, Supriyaa Srinivasan, Devasena Prithviraj, R J Family Med Prim Care Case Series Acute gastroenteritis is an important cause of preventable acute kidney injury (AKI). Inadequate or delayed restoration of diarrheal losses results in a very high incidence of AKI. Diarrheal illness is a major reason for hospitalization, but data on consequent acute kidney injury are sparse. The objective of the study is to determine the incidence of AKI in infectious and noninfectious diarrheal illness requiring hospitalization and to identify correlates and outcomes of diarrhea-associated AKI. None of the patients had any organism isolated in stool, probably due to prompt initiation of antibiotics/inadequate culture growth. Three out of our 6 cases did not require hemodialysis (HD) and AKI resolved on conservative management alone (fluids, electrolyte management, and antibiotics). Three out of 6 cases had nonresolving AKI and were dependent on renal replacement therapy (RRT) even at 1 month after discharge as they remained oliguric. One recent paper has reported the recovery of renal function after a period of dialysis. Frequent electrolyte abnormalities, risk of (catheter-related/bloodstream) infections, and severity of the primary disease are the chief reasons for the persistently high morbidity. Although, there was no mortality in our study. Wolters Kluwer - Medknow 2021-06 2021-07-02 /pmc/articles/PMC8284204/ /pubmed/34322450 http://dx.doi.org/10.4103/jfmpc.jfmpc_1979_20 Text en Copyright: © 2021 Journal of Family Medicine and Primary Care https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Series
Bhakthavatchalam, Supriyaa
Srinivasan, Devasena
Prithviraj, R
The requirement of hemodialysis in patients with acute gastroenteritis–induced acute kidney injury
title The requirement of hemodialysis in patients with acute gastroenteritis–induced acute kidney injury
title_full The requirement of hemodialysis in patients with acute gastroenteritis–induced acute kidney injury
title_fullStr The requirement of hemodialysis in patients with acute gastroenteritis–induced acute kidney injury
title_full_unstemmed The requirement of hemodialysis in patients with acute gastroenteritis–induced acute kidney injury
title_short The requirement of hemodialysis in patients with acute gastroenteritis–induced acute kidney injury
title_sort requirement of hemodialysis in patients with acute gastroenteritis–induced acute kidney injury
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284204/
https://www.ncbi.nlm.nih.gov/pubmed/34322450
http://dx.doi.org/10.4103/jfmpc.jfmpc_1979_20
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