Cancer and COVID-19: analysis of patient outcomes

Background: We sought to investigate the outcomes associated with COVID-19 disease in cancer patients. Methods: We conducted a retrospective cohort study of laboratory-confirmed COVID-19 patients. Results: Of the 206 patients included, 57 had at least one preexisting malignancy. Cancer patients were...

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Detalles Bibliográficos
Autores principales: Aboueshia, Mohamed, Hussein, Mohammad Hosny, Attia, Abdallah S, Swinford, Aubrey, Miller, Peter, Omar, Mahmoud, Toraih, Eman Ali, Saba, Nakhle, Safah, Hana, Duchesne, Juan, Kandil, Emad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284249/
https://www.ncbi.nlm.nih.gov/pubmed/34263660
http://dx.doi.org/10.2217/fon-2021-0121
Descripción
Sumario:Background: We sought to investigate the outcomes associated with COVID-19 disease in cancer patients. Methods: We conducted a retrospective cohort study of laboratory-confirmed COVID-19 patients. Results: Of the 206 patients included, 57 had at least one preexisting malignancy. Cancer patients were older than noncancer patients. Of the 185 discharged cases, cancer patients had a significantly higher frequency of unplanned reintubation (7.1% vs 0.9%, p < 0.049), and required longer hospital stay (8.58 ± 6.50 days versus 12.83 ± 11.44 days, p < 0.002). Regression analysis revealed that obesity and active smoking were associated with an increased risk of mortality. Conclusion: Outcomes in COVID-19 appear to be driven by obesity as well as active smoking, with no difference in mortality between cancer and noncancer patients.

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