Cargando…

TDP-43 and amyloid precursor protein processing: implications for Alzheimer’s disease

Detalles Bibliográficos
Autor principal:	Hicks, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2020
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284272/ https://www.ncbi.nlm.nih.gov/pubmed/33318427 http://dx.doi.org/10.4103/1673-5374.300983

Ejemplares similares

The cellular expression and proteolytic processing of the amyloid precursor protein is independent of TDP-43
por: Hicks, David A., et al.
Publicado: (2020)

TDP-43 overexpression impairs presynaptic integrity
por: Heyburn, Lanier, et al.
Publicado: (2016)

Propagation of TDP-43 proteinopathy in neurodegenerative disorders
por: Keszycki, Rachel, et al.
Publicado: (2021)

Cell senescence, loss of splicing, and lipid metabolism in TDP-43-related neurodegenerative processes
por: Torres, Pascual, et al.
Publicado: (2023)

TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer’s disease and frontotemporal lobar degeneration
por: Foulds, Penelope, et al.
Publicado: (2008)

TDP-43 Pathology in Alzheimer’s Disease
por: Meneses, Axel, et al.
Publicado: (2021)

TDP-35, a truncated fragment of TDP-43, induces dose-dependent toxicity and apoptosis in flies
por: Chhangani, Deepak, et al.
Publicado: (2022)

Targeting amyloid precursor protein shuttling and processing - long before amyloid beta formation
por: Arbor, Sage
Publicado: (2017)

Do not curse the darkness of the spinal cord, light TDP-43
por: Asakawa, Kazuhide, et al.
Publicado: (2020)

TDP-43: From Alzheimer’s Disease to Limbic-Predominant Age-Related TDP-43 Encephalopathy
por: Huang, Wendi, et al.
Publicado: (2020)

Amyloid Precursor Protein (APP) and GABAergic Neurotransmission
por: Tang, Bor Luen
Publicado: (2019)

The important functional role of TDP-43 plays in amyotrophic lateral sclerosis-frontotemporal dementia
por: Chen, Liam
Publicado: (2020)

TDP-43 interacts with amyloid-β, inhibits fibrillization, and worsens pathology in a model of Alzheimer’s disease
por: Shih, Yao-Hsiang, et al.
Publicado: (2020)

Disease‐linked TDP‐43 hyperphosphorylation suppresses TDP‐43 condensation and aggregation
por: Gruijs da Silva, Lara A, et al.
Publicado: (2022)

TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP
por: Arseni, Diana, et al.
Publicado: (2023)

Amyloid Precursor Protein and Alzheimer’s Disease
por: Orobets, Kseniia S., et al.
Publicado: (2023)

Cryo-EM Structures of Four Polymorphic TDP-43 Amyloid Cores
por: Cao, Qin, et al.
Publicado: (2019)

Chemically oligomerizable TDP-43: a novel chemogenetic tool for studying the pathophysiology of amyotrophic lateral sclerosis
por: Kanekura, Kohsuke, et al.
Publicado: (2022)

Chaperone Mediated Autophagy Degrades TDP-43 Protein and Is Affected by TDP-43 Aggregation
por: Ormeño, Fernando, et al.
Publicado: (2020)

TDP-43-regulated cryptic RNAs accumulate in Alzheimer’s disease brains
por: Estades Ayuso, Virginia, et al.
Publicado: (2023)

TDP-43 Epigenetic Facets and Their Neurodegenerative Implications
por: Gimenez, Juliette, et al.
Publicado: (2023)

Implications of TDP-43 in non-neuronal systems
por: Ke, Hao, et al.
Publicado: (2023)

Might Fibroblasts from Patients with Alzheimer’s Disease Reflect the Brain Pathology? A Focus on the Increased Phosphorylation of Amyloid Precursor Protein Tyr(682) Residue
por: Iannuzzi, Filomena, et al.
Publicado: (2021)

TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer’s disease
por: Nag, Sukriti, et al.
Publicado: (2018)

Association of TDP-43 proteinopathy, cerebral amyloid angiopathy, and Lewy bodies with cognitive impairment in individuals with or without Alzheimer’s disease neuropathology
por: Thomas, David X., et al.
Publicado: (2020)

TDP-43 and Limbic-Predominant Age-Related TDP-43 Encephalopathy
por: Zhang, Lumi, et al.
Publicado: (2020)

DCTN1 Binds to TDP-43 and Regulates TDP-43 Aggregation
por: Deshimaru, Manami, et al.
Publicado: (2021)

Intracellular sorting pathways of the amyloid precursor protein provide novel neuroprotective strategies
por: Hermey, Guido
Publicado: (2015)

A pilot exploration with Posiphen to normalize amyloid precursor protein in Down syndrome
por: Chen, Xu-Qiao
Publicado: (2021)

Elucidating the mechanisms of TDP-43 aggregation in a cellular model of motor neuron disease
por: Hicks, David, et al.
Publicado: (2015)

TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle
por: Vogler, Thomas O., et al.
Publicado: (2018)

An Intramolecular Salt Bridge Linking TDP43 RNA Binding, Protein Stability, and TDP43-Dependent Neurodegeneration
por: Flores, Brittany N., et al.
Publicado: (2019)

Copper binding to the Alzheimer’s disease amyloid precursor protein
por: Kong, Geoffrey K.-W., et al.
Publicado: (2007)

TDP-43 Is Elevated in Plasma Neuronal-Derived Exosomes of Patients With Alzheimer’s Disease
por: Zhang, Nan, et al.
Publicado: (2020)

TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins
por: Prpar Mihevc, S., et al.
Publicado: (2016)

Rethinking to riluzole mechanism of action: the molecular link among protein kinase CK1δ activity, TDP-43 phosphorylation, and amyotrophic lateral sclerosis pharmacological treatment
por: Bissaro, Maicol, et al.
Publicado: (2019)

An Amyloid-Like Pathological Conformation of TDP-43 Is Stabilized by Hypercooperative Hydrogen Bonds
por: Mompeán, Miguel, et al.
Publicado: (2016)

TDP-43 stabilises the processing intermediates of mitochondrial transcripts
por: Izumikawa, Keiichi, et al.
Publicado: (2017)

The cooperative binding of TDP-43 to GU-rich RNA repeats antagonizes TDP-43 aggregation
por: Rengifo-Gonzalez, Juan Carlos, et al.
Publicado: (2021)

Rodent Models of TDP-43 Proteinopathy: Investigating the Mechanisms of TDP-43-Mediated Neurodegeneration
por: Gendron, Tania F., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_b5nafp40nq3fjhguv7psblo7pq