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Ribosomal RNA degradation induced by the bacterial RNA polymerase inhibitor rifampicin

Rifampicin, a broad-spectrum antibiotic, inhibits bacterial RNA polymerase. Here we show that rifampicin treatment of Escherichia coli results in a 50% decrease in cell size due to a terminal cell division. This decrease is a consequence of inhibition of transcription as evidenced by an isogenic rif...

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Detalles Bibliográficos
Autores principales: Hamouche, Lina, Poljak, Leonora, Carpousis, Agamemnon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284325/
https://www.ncbi.nlm.nih.gov/pubmed/34099575
http://dx.doi.org/10.1261/rna.078776.121