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Ribosomal RNA degradation induced by the bacterial RNA polymerase inhibitor rifampicin
Rifampicin, a broad-spectrum antibiotic, inhibits bacterial RNA polymerase. Here we show that rifampicin treatment of Escherichia coli results in a 50% decrease in cell size due to a terminal cell division. This decrease is a consequence of inhibition of transcription as evidenced by an isogenic rif...
Autores principales: | Hamouche, Lina, Poljak, Leonora, Carpousis, Agamemnon J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284325/ https://www.ncbi.nlm.nih.gov/pubmed/34099575 http://dx.doi.org/10.1261/rna.078776.121 |
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