Cargando…

Tools for supporting solution scattering during the COVID-19 pandemic

During the COVID-19 pandemic, synchrotron beamlines were forced to limit user access. Performing routine measurements became a challenge. At the Life Science X-ray Scattering (LiX) beamline, new instrumentation and mail-in protocols have been developed to remove the access barrier to solution scatte...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Lin, Lazo, Edwin, Byrnes, James, Chodankar, Shirish, Antonelli, Stephen, Rakitin, Maksim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284406/
https://www.ncbi.nlm.nih.gov/pubmed/34212889
http://dx.doi.org/10.1107/S160057752100521X
_version_ 1783723392372834304
author Yang, Lin
Lazo, Edwin
Byrnes, James
Chodankar, Shirish
Antonelli, Stephen
Rakitin, Maksim
author_facet Yang, Lin
Lazo, Edwin
Byrnes, James
Chodankar, Shirish
Antonelli, Stephen
Rakitin, Maksim
author_sort Yang, Lin
collection PubMed
description During the COVID-19 pandemic, synchrotron beamlines were forced to limit user access. Performing routine measurements became a challenge. At the Life Science X-ray Scattering (LiX) beamline, new instrumentation and mail-in protocols have been developed to remove the access barrier to solution scattering measurements. Our efforts took advantage of existing instrumentation and coincided with the larger effort at NSLS-II to support remote measurements. Given the limited staff–user interaction for mail-in measurements, additional software tools have been developed to ensure data quality, to automate the adjustments in data processing, as users would otherwise rely on the experience of the beamline staff, and produce a summary of the initial assessments of the data. This report describes the details of these developments.
format Online
Article
Text
id pubmed-8284406
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-82844062021-08-02 Tools for supporting solution scattering during the COVID-19 pandemic Yang, Lin Lazo, Edwin Byrnes, James Chodankar, Shirish Antonelli, Stephen Rakitin, Maksim J Synchrotron Radiat Beamlines During the COVID-19 pandemic, synchrotron beamlines were forced to limit user access. Performing routine measurements became a challenge. At the Life Science X-ray Scattering (LiX) beamline, new instrumentation and mail-in protocols have been developed to remove the access barrier to solution scattering measurements. Our efforts took advantage of existing instrumentation and coincided with the larger effort at NSLS-II to support remote measurements. Given the limited staff–user interaction for mail-in measurements, additional software tools have been developed to ensure data quality, to automate the adjustments in data processing, as users would otherwise rely on the experience of the beamline staff, and produce a summary of the initial assessments of the data. This report describes the details of these developments. International Union of Crystallography 2021-06-25 /pmc/articles/PMC8284406/ /pubmed/34212889 http://dx.doi.org/10.1107/S160057752100521X Text en © Lin Yang et al. 2021 https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Beamlines
Yang, Lin
Lazo, Edwin
Byrnes, James
Chodankar, Shirish
Antonelli, Stephen
Rakitin, Maksim
Tools for supporting solution scattering during the COVID-19 pandemic
title Tools for supporting solution scattering during the COVID-19 pandemic
title_full Tools for supporting solution scattering during the COVID-19 pandemic
title_fullStr Tools for supporting solution scattering during the COVID-19 pandemic
title_full_unstemmed Tools for supporting solution scattering during the COVID-19 pandemic
title_short Tools for supporting solution scattering during the COVID-19 pandemic
title_sort tools for supporting solution scattering during the covid-19 pandemic
topic Beamlines
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284406/
https://www.ncbi.nlm.nih.gov/pubmed/34212889
http://dx.doi.org/10.1107/S160057752100521X
work_keys_str_mv AT yanglin toolsforsupportingsolutionscatteringduringthecovid19pandemic
AT lazoedwin toolsforsupportingsolutionscatteringduringthecovid19pandemic
AT byrnesjames toolsforsupportingsolutionscatteringduringthecovid19pandemic
AT chodankarshirish toolsforsupportingsolutionscatteringduringthecovid19pandemic
AT antonellistephen toolsforsupportingsolutionscatteringduringthecovid19pandemic
AT rakitinmaksim toolsforsupportingsolutionscatteringduringthecovid19pandemic