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Tools for supporting solution scattering during the COVID-19 pandemic
During the COVID-19 pandemic, synchrotron beamlines were forced to limit user access. Performing routine measurements became a challenge. At the Life Science X-ray Scattering (LiX) beamline, new instrumentation and mail-in protocols have been developed to remove the access barrier to solution scatte...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284406/ https://www.ncbi.nlm.nih.gov/pubmed/34212889 http://dx.doi.org/10.1107/S160057752100521X |
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author | Yang, Lin Lazo, Edwin Byrnes, James Chodankar, Shirish Antonelli, Stephen Rakitin, Maksim |
author_facet | Yang, Lin Lazo, Edwin Byrnes, James Chodankar, Shirish Antonelli, Stephen Rakitin, Maksim |
author_sort | Yang, Lin |
collection | PubMed |
description | During the COVID-19 pandemic, synchrotron beamlines were forced to limit user access. Performing routine measurements became a challenge. At the Life Science X-ray Scattering (LiX) beamline, new instrumentation and mail-in protocols have been developed to remove the access barrier to solution scattering measurements. Our efforts took advantage of existing instrumentation and coincided with the larger effort at NSLS-II to support remote measurements. Given the limited staff–user interaction for mail-in measurements, additional software tools have been developed to ensure data quality, to automate the adjustments in data processing, as users would otherwise rely on the experience of the beamline staff, and produce a summary of the initial assessments of the data. This report describes the details of these developments. |
format | Online Article Text |
id | pubmed-8284406 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-82844062021-08-02 Tools for supporting solution scattering during the COVID-19 pandemic Yang, Lin Lazo, Edwin Byrnes, James Chodankar, Shirish Antonelli, Stephen Rakitin, Maksim J Synchrotron Radiat Beamlines During the COVID-19 pandemic, synchrotron beamlines were forced to limit user access. Performing routine measurements became a challenge. At the Life Science X-ray Scattering (LiX) beamline, new instrumentation and mail-in protocols have been developed to remove the access barrier to solution scattering measurements. Our efforts took advantage of existing instrumentation and coincided with the larger effort at NSLS-II to support remote measurements. Given the limited staff–user interaction for mail-in measurements, additional software tools have been developed to ensure data quality, to automate the adjustments in data processing, as users would otherwise rely on the experience of the beamline staff, and produce a summary of the initial assessments of the data. This report describes the details of these developments. International Union of Crystallography 2021-06-25 /pmc/articles/PMC8284406/ /pubmed/34212889 http://dx.doi.org/10.1107/S160057752100521X Text en © Lin Yang et al. 2021 https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Beamlines Yang, Lin Lazo, Edwin Byrnes, James Chodankar, Shirish Antonelli, Stephen Rakitin, Maksim Tools for supporting solution scattering during the COVID-19 pandemic |
title | Tools for supporting solution scattering during the COVID-19 pandemic |
title_full | Tools for supporting solution scattering during the COVID-19 pandemic |
title_fullStr | Tools for supporting solution scattering during the COVID-19 pandemic |
title_full_unstemmed | Tools for supporting solution scattering during the COVID-19 pandemic |
title_short | Tools for supporting solution scattering during the COVID-19 pandemic |
title_sort | tools for supporting solution scattering during the covid-19 pandemic |
topic | Beamlines |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284406/ https://www.ncbi.nlm.nih.gov/pubmed/34212889 http://dx.doi.org/10.1107/S160057752100521X |
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